Junior Clinical Research Fellow in Renal Transplantation

Royal Free London NHS Foundation Trust; Greater London; On-site; GBP 35,000 - 45,000; Full time

Job summary

A leading NHS trust in Greater London is seeking a Clinical Research Fellow to support the PROSPECT Study, focusing on renal and liver transplant research. This research role exclusively emphasizes study activities without clinical service commitments. The post-holder will assist with participant recruitment, follow-up, and data management. Ideal candidates should possess a relevant degree and have a strong background in research methodology and data analysis. Join this initiative and gain invaluable experience in a dynamic research environment.

Benefits

Generous benefits

Flexible working hours

Opportunities for professional training

Qualifications

• Experience in conducting research studies, ideally in a clinical environment.
• Familiarity with pharmacokinetics and pharmacodynamics.
• Ability to work with transplant patients and clinical data.

Responsibilities

• Support delivery of Phase 1 and Phase 2 research activity.
• Assist with recruitment and follow-up of participants.
• Conduct data acquisition and sample handling.

Skills

Research methodology

Data analysis

Sample handling

Education

Relevant degree (PhD, MD, or equivalent)

Job description

Applications are invited for a Clinical Research Fellow to support the conduct of the PROSPECT Study – Physiological Response to Once-Daily Tacrolimus (LCP-T) – at the Royal Free Hospital.

This is a fully funded research post delivered within the Renal, Nephrology and Renal Transplant Services, working under the supervision of the Principal Investigator, Dr Rhys Evans. The post-holder will support delivery of Phase 1 and Phase 2 research activity in accordance with the study protocol, NIHR and GCP standards.

The study is supported through research funding provided by Chiesi Ltd to the Royal Free London NHS Foundation Trust. This funding supports research personnel, materials and delivery of study milestones.

This post is exclusively research-focused with no clinical service commitment.

The PROSPECT Study (Physiological Response to Once-Daily Tacrolimus [LCP-T]) is a multi-phase, observational research programme evaluating pharmacokinetics, pharmacodynamics, and immunological responses to once-daily tacrolimus in kidney and liver transplant recipients at the Royal Free Hospital.

Phase 1 includes large-scale metabolomic and biochemical analysis in approximately 600 transplant recipients to characterise drug exposure profiles and identify predictors of variability.

Phase 2 involves detailed sub-study monitoring of 40 transplant patients (20 kidney, 10 liver, 10 control) to explore longitudinal changes in drug exposure, biomarkers and immunological response. The post-holder will assist with recruitment, participant follow-up, data acquisition and sample handling.

This role provides experience in transplant research, specialist assay methodologies and regulated delivery of commercial-supported studies. The PROSPECT Study (Physiological Response to Once-Daily Tacrolimus [LCP-T]) is a multi-phase, observational research programme evaluating pharmacokinetics, pharmacodynamics, and immunological responses to once-daily tacrolimus in kidney and liver transplant recipients at the Royal Free Hospital.

The Royal Free London NHS Foundation Trust is one of the UK’s biggest and most innovative trusts. Across three main hospitals, our dedicated army of staff care for over 1.6million patients, treat more than 200,000 in A&E, deliver over 8,000 babies and carry out more than 17million tests.

Our size, scale and influence offer you unrivalled career opportunities and a forward-thinking approach to working that works around your lifestyle. From flexible hours and generous benefits, to next level training, we make it easier to take your career to the top

For more information please follow link https://www.royalfreelondonjobs.co.uk/

For further details / informal visits contact: Name: Prof Rhys Evans Job title: Clinical Lead for Kidney Transplantation Email address: [e-mail]