Senior Biochemist – Phage Manufacturing and Process Development

Adoc Talent Management; Paris; Hybride; EUR 40 000 - 60 000; Plein temps

Résumé du poste

A biotech recruitment agency is seeking a Senior Biochemist focused on Microbiology and Early CMC in Paris. The role involves developing precision microbiome medicines and transitioning to clinical-stage biotech. Candidates should have a PhD in Biochemistry and strong microbiology expertise, with hands-on experience in bioprocesses. Competitive salary and equity packages are offered with a hybrid work option.

Prestations

Flexible remote-work policy (2 days/week)

Competitive salary and equity packages

Exceptional office/lab environment

Qualifications

• At least 3 years of experience in biotech/CQMO.
• Experience with biologics and purification methods is necessary.
• Hands-on experience with LC-MS is important.

Responsabilités

• Contribute to characterization of bacteria and phages.
• Design and oversee experiments for production and purification.
• Write SOPs and support regulatory documentation.

Connaissances

Microbiology expertise

Biochemistry knowledge

Project management

Problem solving

Chromatography

Analytical method development

Fluent English

Formation

PhD in Biochemistry

Outils

Biorad NGC system

Akta system

Bioreactors

Description du poste

Reference: AMB-ATM24085A| Business sector : Biotech | Contract type : permanent contract | Country : France | Region : Paris Region | City : Paris

Company

We are looking for a Senior Biochemist – Microbiology and Early CMC – Phage Manufacturing and Process Development for our client, a deeptech startup developing the future of precision microbiome medicines to address serious unmet medical needs in the field of inflammatory diseases, infectious diseases and oncology. Co‑founded by scientists and professors from MIT and the Rockefeller University, backed by top‑tier investors and elected as one of the 30 Most Innovative Companies, they are progressing next‑generation precision medicines through in vivo gene editing of the microbiome and synthetic biology. Today, our client is transitioning from a start‑up deeply rooted in innovation to a clinical stage biotech with the objective to bring the lead program to the clinic within the next two years. In this exciting context, we are looking for a high‑performing and enthusiastic Biochemist with microbiology expertise to join the microbiology and early CMC team to support the transition to manufacturing.

Position

In a fast‑paced, international, interdisciplinary and collaborative work environment, you will have a unique opportunity to grow your skillset and apply cutting‑edge technologies to solve real‑world problems and positively impact the lives of patients.

You will join a team of scientists with strong experience in microbiology, molecular biology and manufacturing. You will contribute to the characterization of bacteria, phages and sequence‑specific antimicrobials to support the development of drug candidate, and to the development of USP (fermentation), DSP (purification) and analytical methods to support manufacturing operations.

Thus, you will design, execute, and oversee hands‑on experiments to develop production (USP), purification (DSP) and analytical process / methods and participate to technical transfer USP, DSP and analytical process / methods to cGMP CDMO. Bench work will represent more or less 30% of your duties. You will also write SOPs. As an expert in your field, you will also support the team in building the CMC development plan and in drafting regulatory document sections when needed.

You will coordinate the project, the associated experimental work, the data analysis and presentation and keep an eye on the state of the art in your domain.

Profile

You hold a PhD in Biochemistry with strong Microbiology expertise and at least 3 years of experience, designing and runing experiments, interpreting data, troubleshooting and suggesting alternative approaches.

You demonstrate previous experience in a biologics (ideally bacteriophages or other viral particles) production, purification and associated analytical methods in biotech / CDMO or laboratory. Experience with QMS (Quality management System) is required. You show up deep knowledge and hands‑on experience in the field of biochemistry, especially in chromatography (Biorad NGC system, Akta system, …) purification. Hands‑on experience with bioreactors is a plus. In terms of CMC development, you have experience in designing and analyzing experiments of Liquid chromatography Mass spectrometry (LC-MS) or analytical ultracentrifugation and a proven ability to develop methods, processes and to transfer to external partners (CDMO).

You are fluent in English (mastery of French is not essential) to be able to interact with the team.

At ease managing project and team player, you are recognized for your outstanding organization and problem solving ability. Being result oriented, independent, proactive, creative, rigorous and adaptable are great assets for the missions.

How to apply

The position is to be filled as soon as possible, on a permanent basis. It is based in Paris (flexible remote‑work policy : 2 days per week), in exceptional offices / labs. Competitive salary and equity packages will be proposed.

If joining a passionate, creative, driven team with the aim of developing new drugs to address microbiome‑associated unmet medical needs attracts you : Please send your application (CV, list of publications, patents and scientific works, Google Scholar link, motivation and salary expectations) without further delay to Adoc Talent Management.