Technician - mRNA Process Development

Cipla; Baden-Württemberg; Vor Ort; EUR 50.000 - 70.000; Vollzeit

Zusammenfassung

A leading pharmaceutical company in Germany is seeking a qualified individual to join their mRNA production team. The role involves executing IVT reactions, maintaining lab equipment, and conducting analytical tests. Candidates should possess over 5 years of relevant experience in process development and a degree in biotechnology or life sciences. Strong organizational skills and attention to detail are necessary, with proficiency in English and preferably German. This position offers an exciting opportunity to contribute to innovative mRNA production processes.

Qualifikationen

• 5+ years of experience in process development or relevant field.
• Hands-on experience with IVT, enzymatic reactions, and purification processes.
• Ability to document and communicate effectively in English; German skills are a plus.

Aufgaben

• Perform IVT reactions and enzymatic processing.
• Conduct analytical tests to monitor process performance.
• Operate, clean, and calibrate laboratory instruments.
• Assist scientists in executing experiments and collecting samples.

Kenntnisse

IVT reactions

Enzymatic reactions

Purification processes

Data documentation

English proficiency

Organizational skills

Ausbildung

Bachelor's or Master's degree in biotechnology or related field

Vocational training as BTA or MTA

Jobbeschreibung

Accountability Cluster

Major Activities / Tasks

Accurate Execution of mRNA Production Processes

• Perform IVT reactions
• enzymatic processing
• purification

Reliable Performance of Analytical Methods

• Conduct standard analytical tests to monitor process performance
• UV spectroscopy
• gel electrophoresis
• RNA quantification
• purity assessments

Maintenance of Laboratory Equipment and Work Areas

• Operate, clean, and calibrate assigned instruments;
• ensure workspaces remain organized and compliant with safety standards

Accurate Documentation and Data Recording

• Perform analysis of in-licensed manufacturing process and identify optimization / improvement potential keeping process robustness in mind
• Adapt in-licensed manufacturing processes and controls according to Cipla’s requirements harmonized with clinical development timelines including DNA process
• Build plans for execution of implementation of improvements into in-licensed original process
• Implementation of improvements in alignment with VP and CDO (mRNA)
• Continuous improvement of CMC processes and analytics

Support for Process Optimization and Scale-Up

• Assist scientists in
• executing experiments,
• collecting samples
• compiling results for process improvement studies

Educational qualifications :

• Completed vocational training as a Biological or Medical Technical Assistant (BTA or MTA)
• Alternatively, a Bachelor's or Master's degree in biotechnology, biology, or a related life sciences discipline

Relevant experience :

• 5+ years of experience in process development or relevant field
• Hands-on experience with IVT, enzymatic reactions, and purification processes including tangential flow filtration (TFF).
• Familiarity with molecular biology tools, mRNA handling best practices, and aseptic techniques.
• Strong organizational skills, attention to detail, and the ability to work both independently and in a team.
• Ability to document and communicate effectively in English; German language skills are a plus.