Senior Laboratory Officers Quality Control

Consortium for Clinical Research and Innovation Singapore; Singapore; On-site; SGD 80,000 - 100,000; Full time

Job summary

A leading healthcare research consortium in Singapore seeks a QC Laboratory Officer to ensure compliance with regulatory, GMP, and safety guidelines in cell therapy manufacturing. You'll perform QC-related activities, maintain cleanroom standards, and support documentation and testing processes. The ideal candidate has a degree in a relevant field, prior QC experience, and strong analytical skills. A team-oriented, detail-oriented approach is essential. This position offers a 3-year renewable contract with the opportunity to make a significant impact in innovative healthcare solutions.

Qualifications

• Prior experience with QC techniques like cell count and potency testing.
• Able to perform aseptic gowning in GMP cleanroom for long hours.
• Proficient in English and good communication skills required.

Responsibilities

• Perform cell therapy manufacturing procedures following safety guidelines.
• Maintain cleanroom activities including inventory planning and environmental monitoring.
• Perform QC in-process and final product testing and documentation.

Skills

Cell culture

Flow cytometry

ELISA testing

Analytical thinking

Team collaboration

Education

Degree / Diploma in Life Sciences, Microbiology, Chemistry

Tools

FACSLyric

MACSQuant

Quantstudio

Job description

Overview

The Consortium for Clinical Research and Innovation, Singapore (CRIS) brings together seven national R&D, clinical translation and service programmes to advance clinical research and innovation for Singapore, and establish important capabilities for a future‑ready healthcare system.

The Business Entities under CRIS include:

• Singapore Clinical Research Institute (SCRI)
• National Health Innovation Centre (NHIC)
• Advanced Cell Therapy and Research Institute, Singapore (ACTRIS)
• Precision Health Research, Singapore (PRECISE)
• Singapore Translational Cancer Consortium (STCC)
• Cardiovascular Disease National Collaborative Enterprise (CADENCE)
• SIngapore Medical FOundation AI model (SIMFONI)

Together, CRIS makes a positive difference to Singapore patients and researchers by ensuring that these clinical research platforms and programmes are at the cutting edge of capability development and innovation. If you are as passionate as we are in clinical trials and research, we want you!

ACTRIS

The Advanced Cell Therapy and Research Institute, Singapore (ACTRIS) was established to meet the increasing clinical demand of using cellular therapeutics to treat various life‑threatening diseases. ACTRIS’ vision is to be the national and regional Centre of Excellence for discovery, process development and manufacturing of cellular‑based therapeutics across the broad spectrum of immunotherapy and regenerative medicine, encompassing both investigational and approval products for the local market. We also provide value‑added services such as workforce training, regulatory facilitation and ancillary material standardization, pertaining to delivery of cellular therapy to patients.

What you will be working on

The QC Laboratory Officer shall perform CTGTP QC related activities in compliance with ACTRIS SOP and relevant GMP and Safety guidelines.

• Perform cell therapy Manufacturing related procedures in compliance with regulatory, GMP and safety guidelines
• Responsible for all aspects of cleanroom activities such as inventory planning, environmental monitoring and facility/equipment sanitisation with a GMP manufacturing setting.
• Ensure proper maintenance and control of manufacturing areas, clean suites and equipment.
• Responsible for accurate and timely documentation of relevant batch records, forms and log sheets for the tasks performed in compliance with GDDP (Good Data and documentation practices).
• Resolve operational issues and escalating when required
• Support root cause analysis, CAPA, OOS, OOT, deviations, and change controls
• Participate in technology transfer and other cross function projects
• Participate in environmental monitoring, microbiological assessment, materials and/or equipment including developing URS, SOPs and as well as providing training related to laboratory methods and/or equipment
• Assist to check equipment PM/service reports, IOQ document and etc to ensure completeness and GDDP compliance
• Assist SLO review of documents such as, PM IOQ documents, QC test reports and log sheets
• Draft and execute PQ for new QC equipment.
• Support / manage QC Lab inventory, as required to ensure there is a continuous supply of the consumables to support the required testing procedure.
• Support / manage QC Lab equipment as required to ensure it is qualified, validated and well maintained to support the required testing procedure.
• Identifying processing gaps, participate or contribute to the team (researcher, cell specialist and project team) in development of new or improvement of existing laboratory test methodologies/instrumentation.
• Maintain good filling system for documentation including equipment, inventory, raw data, test records, deviation report, validation records etc.
• Perform QC in-process and final product testing and analysis independently.
• Other duties and responsibilities as assigned by the RO or HOD.

What we are looking for

EDUCATION, TRAINING

• Degree / Diploma in Life Sciences, Microbiology, Chemistry
• Prior experience with QC techniques such as cell culture, cell count (Sysmex), flow cytometry (FACSLyric, MACSQuant), ELISA testing (Tecan), RT-PCR (Quantstudio), potency, microbiology and/or working in GMP cleanroom will be an advantage.
• Attention to detail and possess analytical thinking skill
• Able to be a team player with good communication skills and strong team orientated work ethic
• Able to perform aseptic gowning and work in GMP cleanroom for long hours
• Proficient in English

What you need to know

Successful candidate will be offered a 3-year contract, renewable. We regret that only shortlisted candidates will be contacted. For more information about CRIS and the Business Entities, visit our websites below:

• CRIS – https://www.cris.sg
• SCRI – https://www.scri.edu.sg
• NHIC – https://www.nhic.sg
• ACTRIS – https://www.actris.sg
• PRECISE – https://www.npm.sg
• STCC – https://www.stcc.sg
• CADENCE – https://www.cris.sg/our-programmes/cadence/