Scientist/Senior, Biotherapeutics Development (BTI)

A*STAR RESEARCH ENTITIES; Singapore; On-site; SGD 80,000 - 100,000; Full time

Job summary

A leading research organization in Singapore is seeking a highly motivated Scientist to join their Biotherapeutics Development group. The role involves characterizing monoclonal antibodies and developing therapeutic candidates for clinical applications. Ideal candidates should have a PhD in relevant fields and experience in cellular biology assays. Strong organizational skills and the ability to work collaboratively with teams are essential. This is a fantastic opportunity to contribute to significant translational research with industry partners.

Qualifications

• PhD degree in relevant disciplines including Biomedical Science or Immunology.
• Familiarity with selection of lead and hit candidates.
• Interest in translational and applied research.
• Experience in cellular and molecular biology.
• Strong organizational and communication skills.
• Ability to work independently and in teams.

Responsibilities

• Characterize and evaluate monoclonal antibodies and their mechanism.
• Contribute to therapeutics development pipeline.
• Conduct in vivo studies including immunizations.
• Work with internal and external collaborators.
• Mentor students and interns.
• Prepare presentation slides and reports.
• Maintain experimental records.
• Support lab operations and safety compliance.

Skills

Cell culture

Flow cytometry

Western blot

ELISA

Immunoprecipitation

Mammalian cell transfection

Immunohistochemistry

Bioassays

Data analysis

Education

PhD degree in Biomedical Science, Cancer Science, Immunology, or relevant disciplines

Job description

Job Description:

We are seeking a highly motivated Scientist to join our Biotherapeutics Development group. The successful candidate will contribute to research activities developing biotherapeutics with a goal towards clinical applications and commercialisation.

Key responsibilities include:

• Characterise and evaluate monoclonal antibodies (mAbs), its antigen target and mechanism of action needed for a pre-clinical dossier
• Contribute to therapeutics development pipeline through hit and lead identification
• Conduct in vivo studies, such as immunisations and tumour xenograft models
• Work in project teams with internal and external collaborators
• Contribute to mentorship of students and interns
• Prepare presentation slides, reports, technology disclosures, grant proposals
• Maintain accurate and timely experimental records
• Support routine lab operations, including procurement, equipment maintenance, lab safety compliance, and general housekeeping

Job Requirement:

• A PhD degree in Biomedical Science, Cancer Science, Immunology, or relevant disciplines
• Familiar with the requirements needed for selection of potential lead and hit candidates
• A strong interest in the translational and applied aspects of research, including collaborations with industry partners.
• Practical experience in cellular and molecular biology (such as cell culture, flow cytometry, western blot, ELISA, immunoprecipitation, mammalian cell transfection, immunohistochemistry, bioassays, and data analysis) and in vivo studies
• Strong organisational and communication skills
• Able to work independently and collaboratively in a team

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.