QC Senior Chemist

ThermoFisher Scientific; Singapore; On-site; SGD 70,000 - 90,000; Full time

Job summary

A global scientific company in Singapore seeks a Senior QC Chemist to ensure analytical solutions and regulatory compliance in Quality Control. Responsibilities include overseeing lab operations, method validations, and ensuring quality culture. Candidates should have at least 5 years of experience in pharmaceutical QC, strong cGMP knowledge, and a bachelor's degree in relevant fields. Excellent communication skills and audit readiness are essential for this role.

Qualifications

• Minimum 5 years in pharmaceutical/biotech Quality Control.
• Knowledge of FDA, EMA, HSA, PIC/S, and ICH regulations.
• Experience with method transfer and validation.

Responsibilities

• Support new equipment qualification and lab systems.
• Prepare technical documentation (protocols, SOPs, reports).
• Conduct analysis of raw materials and finished products under cGMP.
• Manage daily lab operations in compliance with GMP.
• Train and maintain training records for team members.

Skills

cGMP knowledge

Quality Control chemistry techniques (HPLC, UPLC, CE)

Excellent communication skills in English

Cross-functional collaboration

Audit readiness

Education

Bachelor’s degree in Chemistry, Biochemistry, or Life Sciences

Tools

HPLC

UPLC

Job description

Work Schedule

Standard (Mon-Fri)

Environmental Conditions

Adherence to all Good Manufacturing Practices (GMP) Safety Standards, Laboratory Setting, Office, Some degree of PPE (Personal Protective Equipment) required (safety glasses, gowning, gloves, lab coat, ear plugs etc.)

Job Description

Position Summary

Join Thermo Fisher Scientific’s Quality Control team as a Senior QC Chemist. You will ensure cGMP and regulatory compliance while delivering analytical solutions through expertise in biologics chemistry, method qualification/validation, and timely project completion. Responsibilities include overseeing lab activities, leading investigations, and promoting quality culture and compliance across the site.

Responsibilities

• Support new equipment qualification, lab systems, and chemistry lab setup.
• Perform transfer/verification/validation of analytical methods.
• Prepare technical documentation (protocols, SOPs, reports).
• Conduct analysis of raw materials, intermediates, finished products, and stability samples under cGMP.
• Oversee sampling, testing, and release processes for process aids and packaging materials.
• Ensure timely chemistry testing (HPLC, GC, particle counting, etc.) to support production.
• Manage daily lab operations in compliance with GMP and company standards.
• Update processes in response to new pharmacopoeia/regulatory changes.
• Lead lab investigations/deviations and ensure timely closure per Quality System.
• Review analytical data for accuracy and compliance.
• Perform equipment maintenance and calibration.
• Troubleshoot analytical methods and equipment issues.
• Manage QC chemical, reference standard, and consumable inventory.
• Train and maintain training records for team members.
• Stay updated on international regulations (GMP, GLP, ICH, pharmacopoeias).
• Act as SME during audits/inspections.
• Support internal audits, inspections, and continuous improvement.
• Promote Quality Culture and 4i values.
• Adhere to HSE, GMP, and 5S standards.
• Support shift work as needed.

Minimum Requirements/Qualifications

Education

• Bachelor’s degree in Chemistry, Biochemistry, or Life Sciences.

Experience

• Minimum 5 years in pharmaceutical/biotech Quality Control.
• Knowledge of FDA, EMA, HSA, PIC/S, and ICH regulations.
• Strong cGMP knowledge and QC chemistry techniques (HPLC, UPLC, CE).
• Experience with method transfer and validation.
• Excellent communication skills in English.
• Ability to work cross-functionally and under regulatory scrutiny.
• Audit and inspection readiness experience.

Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.