Scientist, Assay Development (Contract)

Flagship Pioneering; Peterborough; On-site; GBP 50,000 - 70,000; Full time

Job summary

A leading bioplatform innovation company in Peterborough is seeking a motivated Assay Development Scientist. In this role, you'll drive innovation in NGS workflows and lead the implementation of advanced technologies for somatic genomics. You should have a BSc or MSc in a relevant field and at least 8 years of experience in NGS research. The ideal candidate will excel in project management and have a proven record of developing novel solutions for complex challenges. Competitive salary offered.

Qualifications

• Minimum 8 years' post-graduation experience in NGS workflow research and development and/or spatial genomics.
• Excellent communication skills, both written and verbal.
• A high degree of energy, accuracy and attention to detail.

Responsibilities

• Conduct bench-based experiments.
• Drive innovation in core NGS library preparation methods.
• Lead piloting and implementation of spatial biology/single-cell platforms.

Skills

NGS workflow research

PCR workflow design and optimization

Spatial transcriptomics

Communication skills

Attention to detail

Education

BSc or MSc in biochemistry, molecular biology, or microbiology

Tools

Notion

Trello

Jira

Job description

Assay Development Scientist

We are seeking a motivated, enthusiastic Assay Development Scientist to join our passionate team. The role will drive innovation in Quotient's NGS workflows and lead the implementation of spatial biology/single‑cell technologies for our somatic genomics platform.

Responsibilities

• Conduct bench‑based experiments.
• Drive innovation in core next‑generation sequencing (NGS) library preparation methods.
• Lead piloting and implementation of spatial biology/single‑cell platforms at Quotient.
• Manage cross‑functional teams to deliver complex projects and model good practice in project management.
• Explore the scientific literature and propose innovative new tools or methods to support Quotient's overarching goals.
• Advise senior management on strategic decision‑making.
• Develop standard operating procedures for new versions of assays to enable smooth transfer of processes to Quotient's high‑throughput laboratory.
• Maintain compliance with regulatory requirements and quality standards, including the Human Tissue Act and COSHH.
• Collaborate and communicate with other team members across various functional areas.

Qualifications

• BSc or MSc in biochemistry, molecular biology, microbiology, or a related field.
• Minimum 8 years' post‑graduation experience in NGS workflow research and development and/or spatial genomics.
• Experience in the design and optimisation of PCR workflows.
• Hands‑on experience in the implementation and troubleshooting of spatial transcriptomics and/or single‑cell platforms such as 10X Xenium or Chromium.
• Evidence of devising novel solutions to research challenges and driving technological innovation.
• Knowledge and experience of working under HTA regulations.
• Excellent communication skills, both written and verbal.
• Experience working with digital productivity tools such as Notion, Trello or Jira.
• A high degree of energy, accuracy and attention to detail, and a passion for contributing to work leading to transformative medicines for patients with serious diseases.

Desirable

• Experience in the isolation and handling of RNA, especially for NGS library preparation.
• Experience with laboratory information management systems (Benchling preferred).
• Experience with histological processing of human tissues.
• Previous experience in a biotech or pharmaceutical industry setting.
• PhD in a relevant discipline.

Postdoctoral Research Scientist – David Group, Babraham Institute, Cambridge

We are seeking an enthusiastic and talented Postdoctoral Research Scientist to join the David group at the Babraham Institute. Our overarching goal is to discover mechanisms that promote healthy ageing and alleviate age‑related diseases such as Alzheimer’s.

Qualifications

• BSc or MSc in biochemistry, molecular biology or microbiology, or a related field.
• Minimum of 8 years' post‑graduation experience in NGS workflow research and development and/or spatial genomics.
• Experience in the design and optimisation of PCR workflows.
• Hands‑on experience in the implementation and troubleshooting of spatial transcriptomics and/or single‑cell platforms, such as 10X Xenium or Chromium.
• Evidence of an ability to devise novel solutions to research challenges and drive technological innovation.
• Knowledge and experience of working under HTA regulations.
• Excellent communication skills, both written and verbal.
• Experience working with digital productivity tools such as Notion, Trello or Jira.
• A high degree of energy, accuracy and attention to detail, and a passion for contributing to work leading to the creation of transformative medicines for patients with serious diseases.

Desirable

• Experience in the isolation and handling of RNA, especially for NGS library preparation.
• Experience with laboratory information management systems (Benchling preferred).
• Experience with histological processing of human tissues.
• Previous experience in a biotech or pharmaceutical industry setting.
• PhD in a relevant discipline.

Company Overview

Quotient Therapeutics Ltd is a privately held, early‑stage company developing a novel genomics platform and therapeutics for diseases with a large unmet need.

Flagship Pioneering

Flagship Pioneering is a bioplatform innovation company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability.

Equal Employment Opportunity Statement

Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

Recruitment & Staffing

Flagship Pioneering and its affiliated Flagship Lab companies (collectively, "FSP") do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.