Research Associate

University of York; York and North Yorkshire; On-site; GBP 30,000 - 40,000; Full time

Job summary

A leading research university in the UK is inviting applications for a full-time postdoctoral research associate in the Department of Chemistry. This role focuses on developing a programmable multienzyme assembly for enzymatic nucleic acid synthesis using a multidisciplinary approach. Candidates should hold a PhD in relevant fields and demonstrate expertise in replication/transcription biochemistry, enzyme engineering, and more. Excellent communication skills and a collaborative ethos are also essential.

Qualifications

• PhD or equivalent in relevant field is essential.
• Hands-on experience in designing and analysing protein/peptide libraries is required.
• Excellent communication skills for scientific writing are needed.

Responsibilities

• Develop programmable multienzyme assembly for nucleic acid synthesis.
• Characterise using multidisciplinary approaches including smFRET and mass spectrometry.

Skills

Replication/transcription biochemistry

Multienzyme systems

Enzyme engineering

Nucleic acids synthesis

Scientific communication

Protein/peptide library design

Education

PhD in biochemistry, bioengineering, structural biology or equivalent

Job description

Overview

Dr Purba Mukherjee invites applications from motivated individuals for a full-time postdoctoral research associate position in the Department of Chemistry. The position is funded by an EPSRC Open Fellowship with an initial term of 18 months with potential for extension.

Department

The Department of Chemistry is one of the largest and most successful departments at York and we are renowned internationally for our research. As a department, we strive to provide a working environment that allows all staff and students to contribute fully, to flourish, and to excel. We are proud of our Athena Swan Gold Award.

Role

You will be involved in developing a programmable multienzyme assembly for enzymatic nucleic acid synthesis characterised using a multidisciplinary approach including protein library design, single-molecule FRET (smFRET), mass spectrometry, enzyme kinetics and atomic force microscopy (AFM). Knowledge of nucleic acid-modifying enzymes, specifically DNA/RNA polymerases, and enzymatic protein assemblies is essential.

Skills, Experience & Qualifications needed

• A PhD in biochemistry, bioengineering, structural biology or equivalent experience
• Excellent knowledge in replication/transcription biochemistry to engage in high-quality research
• Enthusiasm for multidisciplinary research related to multienzyme systems, enzyme engineering and nucleic acids synthesis
• Collaborative ethos, positive attitude and committed to personal development
• Hands-on experience in designing, generating and analysing a protein/peptide library
• Excellent oral scientific communication skills and able to write up research work for publication
• Commitment to values of equality, diversity and inclusion

Interview date

To be confirmed

For informal enquiries

For informal enquiries, please contact Dr Purba Mukherjee, email [e-mail]

The Department of Chemistry values all employees for the qualities and skills they bring to the workplace and aims to be a diverse and egalitarian community in which all can thrive.