Postdoctoral Researcher in Myeloid Neoplasms (MPNs) and Blast Phase MPN

University of Oxford; Oxford; On-site; GBP 30,000 - 50,000; Full time

Job summary

A leading research institution in Oxford is seeking a motivated researcher to join a major programme focused on understanding disease progression in myeloproliferative neoplasms. The ideal candidate will have a relevant PhD/DPhil and experience in haematopoiesis, molecular biology, and genomics. Responsibilities include leading wet lab experiments and collaborating with a multidisciplinary team to generate insightful datasets aimed at identifying novel biomarkers. This role offers an opportunity to contribute to impactful biomedical research.

Qualifications

• PhD/DPhil with expertise in haematopoiesis research.
• Experience in molecular biology and single cell genomics essential.
• First author on high-impact papers in leukaemia biology.

Responsibilities

• Lead wet lab experimentation using single-cell multiomic approaches.
• Work with clinicians and scientists to generate high-resolution datasets.

Skills

Haematopoiesis research

Molecular biology

Genomics

Data analysis

Single cell genomics

Education

Relevant PhD/DPhil

Job description

Overview

Radcliffe Department of Medicine, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Headington, Oxford. We are seeking a talented and motivated researcher to join the Mead Group to contribute to a major research programme focused on understanding and preventing disease progression in myeloproliferative neoplasms (MPNs). The role would suit an ambitious, proactive and detail-oriented individual, with experience in haematopoiesis research, molecular biology and genomics, with a passion for applying their skills to improve patient outcomes through impactful biomedical research.

Responsibilities

• You will take a lead role in conducting wet lab experimentation, applying state-of-the-art single-cell multiomic approaches and functional genomic screens to patient-derived samples and disease models.
• Working closely with a dynamic and multidisciplinary team of clinicians and scientists, you will help generate and interpret high-resolution datasets that reveal new insights into disease progression, with the ultimate aim of identifying novel biomarkers and therapeutic targets.

Qualifications

• You will hold a relevant PhD/DPhil, together with sufficient specialist knowledge in normal and malignant haematopoiesis research.
• Experience of molecular biology, single cell genomics and/or spatial transcriptomics techniques and data analysis will be essential.
• First author high-impact papers in the field of leukaemia biology.