In Vivo Scientist II

Insmed; Cambridge; On-site; GBP 60,000 - 90,000; Full time

Job summary

A global biopharmaceutical company in Cambridge is seeking an experienced in vivo Scientist to advance drug discovery programs. The role involves collaborating with cross-functional teams, conducting in vivo studies, and leading improvements in workflow efficiencies. Ideal candidates will have over 5 years of experience and a UK Home Office Licence. This position offers a competitive compensation package and comprehensive health benefits.

Benefits

Flexible work approach

Comprehensive health insurance

Competitive compensation package

Equity Awards

Employee Stock Purchase Plan

Qualifications

• 5+ years in a relevant scientific discipline with in vivo models.
• Proven in vivo experience with animal models.
• Experience in tissue collection for CNS studies.

Responsibilities

• Work with program leads on overall in vivo project plans.
• Implement and evaluate in vivo studies.
• Prepare study reports and regulatory documents.

Skills

in vivo models

neurodegenerative disease experience

attention to detail

analytical skills

Education

5+ years in a relevant scientific discipline

UK Home Office Licence holder

Job description

Overview

Insmed is a global biopharmaceutical company on a mission to transform the lives of patients living with serious and rare diseases. Our most valuable resource is our employees, and everything we do is motivated by a patients-first mentality. Guided by our core values of collaboration, accountability, passion, respect, and integrity, we aim to foster an inclusive, diverse, and flexible work environment, where our employees are recognized for leaning in and rolling up their sleeves. If you share our vision and want to work with the most dedicated people in the biopharma industry, come to Insmed to accelerate your career.

Recognitions: Consistently Ranked Science’s Top Employer. A Certified Great Place to Work. Insmed is committed to creating a collaborative environment where our team can thrive and be recognized for our efforts.

Summary

This is an outstanding opportunity for an experienced in vivo Scientist to join the Insmed Innovation in vivo team and work closely with cross-functional teams situated in Babraham Cambridge. You will develop a vision on how the in vivo team can support all aspects of early target identification, target validation, and drug discovery programs. You will thrive in a fast-paced, collaborative, multidisciplinary team with the mission of validating proprietary targets and contributing to drug discovery programs.

Responsibilities

• Work with program leads and senior leadership on overall in vivo project plans.
• Support the design, implementation, and evaluation of in vivo studies (in-house and with CROs) to enable target identification, target validation, and drug discovery across projects.
• Plan and execute lab-based work and analyze endpoint data including mouse-model characterization (image and behavior methods), efficacy studies, and small-scale PK/PD studies.
• Prepare study reports, summaries, and regulatory documents.
• Lead continuous improvement activities, applying problem-solving to identify workflow efficiencies and implement technology solutions to enhance processes.
• Collaborate with internal stakeholders to capture learning and incorporate it into processes and practices.
• Contribute to a vibrant and innovative working environment where improvements and new ideas are adopted and shared among teams.
• Work with Bioinformatics and Human Genetics teams to gain an integrated biological understanding of target biology and disease role.
• Provide scientific coaching and mentorship within the matrix-based team.

Qualifications

• 5+ years in a relevant scientific discipline with in vivo models, experience with both in-house and external partners. Neurodegenerative disease experience is advantageous. Scientist I level consideration may be made.
• UK Home Office Licence holder with proven in vivo experience and skills working with animal models.
• Experience with mouse model characterization such as behavior phenotyping and/or image-based analysis.
• Experience planning and executing efficacy studies, including complex dosing routes (IT, ICV, ICM) and cannulation placement for repeat dosing in mice.
• Experience in tissue collection for CNS studies (e.g., spinal cord, brain regions) and sample processing for histology.
• Understanding of regulated procedures and Home Office licence requirements, with welfare advice and support for ongoing projects.
• Experience managing complex external collaborations and partnerships to achieve project goals.
• Strong attention to detail, analytical skills, and understanding of statistical methods; experience with reports, summaries, electronic database entries, and regulatory documents.

Benefits

• Flexible approach to how we work
• Comprehensive health insurance and time-off plans
• Competitive compensation package, including bonus
• Equity Awards (Long-Term Incentives)
• Employee Stock Purchase Plan (ESPP)

Additional Information

Insmed Incorporated is an Equal Opportunity employer. We do not discriminate in hiring on the basis of physical or mental disability, protected veteran status, or any other characteristic protected by law. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law.

Unsolicited resumes from agencies should not be forwarded to Insmed. Insmed will not be responsible for any fees arising from the use of resumes through this source. The Human Resources department is responsible for all recruitment activities; please contact us directly to be considered for a formal agreement.

Insmed is committed to providing access, equal opportunity, and reasonable accommodation for individuals with disabilities in employment, its services, programs, and activities. To request reasonable accommodation to participate in the job application or interview process, please contact us by email [e-mail] and let us know the nature of your request and your contact information. Requests for accommodation will be considered on a case-by-case basis. Please note that only inquiries concerning a request for reasonable accommodation will be responded to from this email address.

Applications will close on 26th September 2025.