Clinical Research Nurse

University of Oxford - Division of Cardiovascular Medicine; Oxford; On-site; GBP 100,000 - 125,000; Full time

Job summary

A leading academic institution in Oxford is looking for a Clinical Research Nurse to support cardiovascular studies. Responsibilities include patient recruitment, conducting research per guidelines, and coordinating studies. Candidates should be registered nurses with relevant experience in clinical settings and strong communication skills. Training in Good Clinical Practice is required.

Benefits

Competitive benefits

Support for professional development

Qualifications

• Experience in clinical setting with an understanding of cardiac diseases.
• Competency in basic laboratory skills including processing blood samples.
• Experience nursing or caring for patients in clinical settings.

Responsibilities

• Support patient recruitment and consent for cardiac research studies.
• Conduct clinical research while adhering to GCP guidelines.
• Coordinate non-complex observational studies and report findings.

Skills

Clinical research experience

Ability to work autonomously

Attention to detail

Excellent communication skills

Education

Registered Nurse; NMC registration

Degree in Biological Sciences

Good Clinical Practice (GCP) training

Job description

Go back University of Oxford - Division of Cardiovascular Medicine

Clinical Research Nurse

The closing date is 07 October 2025

We are seeking a highly motivated Clinical Research Nurse orClinical Research Practitioner (CRP) to join our friendly and approachableResearch Nurse and Support Team (RN&ST) within the internationallyacclaimed Division of Cardiovascular Medicine, renowned for its excellence inclinical research.

The post holder will report to the CVM lead nurse andprovide support for CVM research studies across its three clinical researchfacilities [OCMR, CCRF, AMIIC] as well as the clinical cardiac facilities ofOxford University Hospital Trust Heart Centre, where they will hold an honorarycontract.

The post holder will be responsible for supporting theidentification, pre-screening, recruitment, and consent of patients into alltypes of cardiac research studies from observational to commercial clinicaltrials. The role will involve carrying out key practical elements of researchdelivery, including accurate data collection, blood sampling and processing.They will support study co-ordinators and principle investigators, contributingto the set-up and co-ordination of new studies and take responsibility for asmall portfolio of non-complex observational studies.

Informal visits to prior to application are welcomed and strongly encouraged. Please contactCatherine Krasopoulos: [e-mail]

Main duties of the job

To undertake safe, high-quality, participant-focusedresearch in accordance with Good Clinical Practice guidelines and theResearch Governance Framework for Health and Care.

On the direction of the RN&ST LeadNurse/Manager, work independently within the team, planning ones own workload,as well as contributing towards decision-making.

Act as a study lead/coordinator for a smallportfolio of non-complex observational academic studies. Be responsible for allaspects of these studies including; pre-screening activities, recruitment,assessment, planning, implementing and evaluation of participant care duringparticipation in clinical research visits, ensuring regular feedback to theRN&ST Lead Nurse/Manager and Principal Investigator.

Provide support and/or cover for other CVMedstudies, staff, or service needs as required.

Facilitate and participate (within theboundaries of ones personal competency) in informed consent proceduresappropriate to patient age and understanding, demonstrating GCP principles andadherence to research regulations/University of Oxford SOPs.

Provide and receive sensitive informationrelating to participant involvement in research, ensuring general written andverbal information is clearly conveyed to patients and families regarding studyobjectives, scientific rationale, treatment investigations, side effects, andfollow-up.

About us

The Medical SciencesDivision is an internationally recognized centre of excellence for biomedicaland clinical research and teaching, and the largest academic division in theUniversity of Oxford. It includes 11 clinical departments, 5 non-clinicaldepartments and two Institutes/Centres.

World-leading programmes,housed in state-of-the-art facilities, cover the full range of scientificendeavour from the molecule to the population. With our NHS partners we alsofoster the highest possible standards in patient care.

The Division of Cardiovascular Medicine comprises approximately 170 people across arange of staff groups and locations and has a total turnover of approximately£18M per annum of which external grants amount to around £11M on a total grantportfolio of around £79M. Professor StefanNeubauer is the Head of the Division of Cardiovascular Medicine.

The Division was returned as partof the Clinical Medicine unit of assessment in the 2021 REF, with 59% ofresearch in this area rated as 4* (the highest quality, defined asworld-leading) and a further 34% returning a 3* rating (internationallyexcellent).

The University of Oxford offersan attractive range of competitive benefits available to all staff for bothwork and personal life - https://hr.admin.ox.ac.uk/staff-benefits

Job responsibilities

Responsibilities

To undertake safe, high-quality, participant-focusedresearch in accordance with Good Clinical Practice (GCP) guidelines and theResearch Governance Framework for Health and Care.

On the direction of the RN&ST LeadNurse/Manager, work independently within the team, planning ones own workload,as well as contributing towards decision-making.

Providesupport to study co-ordinators and Principle Investigators involved in theCVMed commercial study portfolio, assisting with study activities as required.

Act as a study lead/coordinator for a smallportfolio of non-complex observational academic studies. Be responsible for allaspects of these studies including; pre-screening activities, recruitment,assessment, planning, implementing and evaluation of participant care duringparticipation in clinical research visits, ensuring regular feedback to theRN&ST Lead Nurse/Manager and Principal Investigator.

Provide support and/or cover for other CVMedstudies, staff, or service needs as required.

Facilitate and participate (within theboundaries of ones personal competency) in informed consent proceduresappropriate to patient age and understanding, demonstrating GCP principles andadherence to research regulations/University of Oxford SOPs.

Provide and receive sensitive informationrelating to participant involvement in research, ensuring general written andverbal information is clearly conveyed to patients and families regarding studyobjectives, scientific rationale, treatment investigations, side effects, andfollow-up.

Work collaboratively within a widermulti-disciplinary study team to ensure effective and professional delivery ofa high standard of care for all study participants/clinical patients within theDivision of Cardiovascular Medicine.

Respond quickly and appropriately to enquiriesand queries using ones own professional judgement to identify when to escalateissues and seek senior support/guidance. Be aware of the regulations aroundreporting adverse events and serious adverse events.

Support senior staff in the management ofpatient/participant emergency situation, in line with locally agreed policiesand standard operating procedures.

Supervise the work of junior/less experiencedstaff, helping to ensure that participant/patient safety is always maintained.

Assist the RN&ST Lead Nurse/Manager inpromoting the work of the RN&ST, as well as involvement in patientengagement and involvement activities.

To be aware of, and adhere to, all locallyagreed policies and standard operating procedures (SOPs) as supplied by OCMR,CCRF and the Division of Cardiovascular Medicine, as well as undertakemandatory training as required by the Oxford University Hospital NHS Trust(OUH).

Complete a portfolio of evidence demonstratingdevelopment of skills based on a competency framework agreed during induction.Continue to achieve individually tailored objectives as agreed by the linemanager following completion of relevant competencies/training.

Adhere to CVM dress code when workingclinically, and the Oxford University protective policies when working in theonsite satellite laboratory.

Onthe request of RN&ST Research Nurse/Manager:

Assist and support studies within the CVM RN&ST,or other CVM research groups, at various stages of the research process fromstudy set-up, pre-screening and recruitment, to study visits, study follow-upand study close out, in accordance with individual research protocols andfollowing standard operating procedures.

Provide support to researchers and radiographersperforming cardiac MRI/CT, including; undertaking and observing safetyscreening procedures and reporting concerns to the research team/radiographers,helping with the process of scan set up and positioning within the scanner,attending participants personal needs, and providing participants with supportand reassurance.

Assist researchers with clinical researchprocedures such as six-minute walk tests, exercise tests/cardio-pulmonaryexercise tests, echocardiography. Training to be provided.

Carry out standard observations such as height,weight, BP, HR, oxygen saturations, urinalysis and ECG, accurately recordingdata as per study protocol, having an awareness of normal and abnormal values,and escalating concerns to senior members of staff.

Perform phlebotomy/cannulation and obtain bloodsamples in line with study protocols.

With training, undertake basic laboratory skillsfor sample processing including; centrifugation, pipetting, sample storage andshipping, ensuring that lab activities are in-line with departmental health andsafety requirements.

Undertake administrative activities, such as theprinting and postage of participant invitation packs, scheduling study visits,managing a calendar, arranging taxi bookings, shipment of study samples, studyexpense reimbursement and invoicing, the distribution of departmental and NIHRresearch surveys, and study close out and archiving.

Maintainhigh-quality and accurate study data within study documentation/case reportforms, ensuring that any adverse or unexpected clinically relevant events arereported in a timely manner and in accordance to the protocol.

Maintain a safe, hazard free workingenvironment, ensuring that all clinical and laboratory areas are clean, tidy,and adequately stocked.

From time to time, assist with the NHS clinicallist, or undertake other duties that are commensurate with the duties andresponsibilities of the post.

Person Specification

Experience

• Clinical and/or clinical research experience within a clinical setting with basic understanding of cardiac diseases
• Experience in dealing with confidential patient information
• Previous experience nursing / caring for patients in a clinical setting.
• Previous experience working with clinical research trials.
• Experience of processing blood samples/ basic laboratory skills

Training

• Human Tissue Act training
• Evidence of training and competency in venepuncture and cannulation

Knowledge and skills

• Well-developed clinical skills including evidence of training and competency in recording ECGs
• Good command of written and spoken English, with the ability to communicate confidential or complex information in a manner, which may require empathy, encouragement and reassurance.
• Ability to work autonomously and exercise own initiative when dealing with common issues within own area of work as well as within a multidisciplinary team
• Ability to organise and manage time effectively as well as maintain a high level of organisational skill to keep to deadlines.
• Excellent attention to detail. Able to evidence keeping well documented and up to date archives/care plans and high-quality records.
• Evidence of continuing professional development and a willingness to undertake further training where necessary.

Qualifications

• Registered Nurse; entry on part 1 (adult) of the NMC register. [please state PIN number, NMC entry date and revalidation date], or Clinical Research Practitioner, please state AHCS registration date and re-accreditation date if applicable.
• Degree in relevant subject e.g. Biological Sciences
• Good Clinical Practice (GCP) training, demonstrate within application.

Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

University of Oxford - Division of Cardiovascular Medicine