Associate Director, Small Molecule Chemistry Development

ASTRAZENECA UK LIMITED; Macclesfield; On-site; GBP 75,000 - 95,000; Full time

Job summary

A leading biopharmaceutical company is seeking an Associate Director for Chemistry in Macclesfield. This role involves leading a team focused on synthetic drug substance process development, mentoring scientists, and driving regulatory submissions. The ideal candidate has a degree in Chemistry with demonstrated people leadership skills and experience in developing commercially viable manufacturing processes. The company fosters innovation and offers a flexible working environment to support impactful contributions towards life-changing medicines.

Qualifications

• Demonstrated experience in synthetic drug substance process development.
• Evidence of people leadership skills through previous responsibilities.
• Track record of leading development and scale-up of synthetic chemistry.
• Good understanding of the drug development process.
• Proven experience in authoring module 3.2 regulatory submissions.

Responsibilities

• Lead a team in synthetic process development and scale-up assessment.
• Drive CMC regulatory submissions and act as reviewer.
• Coach and mentor team members for professional development.
• Contribute to the Chemistry development strategy and improve capabilities.

Skills

Leadership of scientists

Synthetic drug substance process development

Coaching and mentoring

Project management skills

Education

Degree in Chemistry or equivalent experience

Tools

Regulatory submission authoring

Analytical chemistry knowledge

Job description

A leading biopharmaceutical company is seeking an Associate Director for Chemistry in Macclesfield. This role involves leading a team focused on synthetic drug substance process development, mentoring scientists, and driving regulatory submissions. The ideal candidate has a degree in Chemistry with demonstrated people leadership skills and experience in developing commercially viable manufacturing processes. The company fosters innovation and offers a flexible working environment to support impactful contributions towards life-changing medicines.