Postdoctoral position in molecular genetics (M/F)

CNRS; France; Sur place; EUR 30 000 - 40 000; Plein temps

Résumé du poste

A leading research organization in France seeks a First Stage Researcher focused on biomolecular condensates and RNP condensates. The role requires expertise in Drosophila genetics and advanced imaging. You will conduct cutting-edge research within a stimulating international environment. This full-time position starts on January 1, 2026, with an application deadline of December 8, 2025.

Qualifications

• Expertise in Drosophila genetics is mandatory.
• Strong understanding of RNA biology required.
• Proficiency in imaging techniques expected.

Responsabilités

• Conduct research on biomolecular condensates.
• Utilize genetics and chemical approaches to study RNP condensates.
• Participate in meetings and write research manuscripts.

Connaissances

Drosophila genetics

Molecular biology

Advanced imaging

Oral presentation

Description du poste

Organisation/Company CNRS Department Institut de Génétique Humaine Research Field Biological sciences Biological sciences » Biology Researcher Profile First Stage Researcher (R1) Country France Application Deadline 8 Dec 2025 - 23:59 (UTC) Type of Contract Temporary Job Status Full-time Hours Per Week 35 Offer Starting Date 1 Jan 2026 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

Biomolecular condensates have recently emerged as fundamental in cell biology, complementing membrane-bound organelles in the organization of cellular functions. Biomolecular condensates are mesoscopic membrane-less organelles that allow the dynamic orchestration of biochemical reactions by restricting them to a confined space. Cytoplasmic RNA-protein (RNP) condensates are a class of biomolecular condensates, classically described as hubs for mRNA regulation. Most RNP condensates are composed of heterogeneous immiscible phases, but how this feature contributes to their biological functions remains largely unexplored. Using germ granules in Drosophila embryos, an outstanding model of RNP condensates, we recently demonstrated the functional compartmentalization of germ granules, translational repression and activation taking place in two distinct phases. The project will focus on dissecting the intricate relationships between RNP condensate architecture and functions. Using genetics, chemical approaches and an advanced system to generate artificial condensates, the candidate will address how mRNA translation contributes to germ granule biphasic architecture and biophysical properties.

• Drosophila genetics
• Molecular biology
• Advanced imaging (super-resolution, single-molecule imaging, FRAP)
• Oral presentation, participation to meetings, writing manuscripts

The Institute of Human Genetics provides a stimulating international research environment; it is fully endowed with state-of-the-art scientific equipment and has direct access to cutting-edge facilities. The IGH is located on the Arnaud de Villeneuve campus, which is part of the Pro-Cycling Employer Programme.

• Expertise in Drosophila genetics
• Expertise in RNA biology
• Strong expertise in imaging
• Capacity to work independently and with the team