Validation Manager

Nexus Life Sciences; Knowsley; On-site; GBP 50,000 - 55,000; Full time

Job summary

A leading pharmaceutical manufacturer in the Merseyside area is seeking an experienced Validation Manager to oversee the site's validation programme. The role involves leading validation activities, ensuring compliance with GMP standards, and supporting new product introductions. The ideal candidate has at least 3 years of hands-on validation experience in pharmaceutical manufacturing and is a strong communicator capable of managing competing priorities. This is a permanent position with a competitive salary range of £50,000 - £55,000 per annum.

Qualifications

• Minimum of 3 years' hands-on validation experience.
• Strong background in pharmaceutical manufacturing validation.
• Proven expertise in ICH Q3D Elemental Impurities and PDE assessments.

Responsibilities

• Lead the planning, execution, and documentation of site validation activities.
• Oversee ICH Q3D Elemental Impurities and PDE/HBEL assessments.
• Conduct risk assessments, deviation reviews, and CAPA evaluations.
• Provide validation expertise to support NPD/NPI projects.
• Contribute to inspection readiness and continuous improvement.

Skills

Pharmaceutical manufacturing validation

GMP compliance

ICH Q3D Elemental Impurities

Change control

Risk assessment

Education

Degree in Life Sciences or Engineering

Job description

Validation Manager - Pharmaceutical Manufacturing

Location: Merseyside / North Liverpool

Permanent | Competitive Salary £50,000 - £55,000 per annum

A leading pharmaceutical manufacturer in the Merseyside / North Liverpool area is seeking an experienced Validation Manager to join their Quality function. This is a key role within a well‑established site, supporting a broad range of validation activities and driving a modern, compliant validation approach across the facility.

The Opportunity

Reporting into the QA & Compliance Manager, you'll take ownership of the site's validation programme, ensuring all activities align with the Validation Master Plan and current industry standards. You'll work closely with cross‑functional teams, support new product introductions, and play a vital role in inspection readiness and continuous improvement.

Key Responsibilities of the Validation Manager

• Lead the planning, execution, and documentation of site validation activities in line with the Validation Master Plan, covering cleaning, process, mixing, filling, and re‑validation.
• Oversee ICH Q3D Elemental Impurities and PDE/HBEL assessments, ensuring compliance with current regulatory expectations.
• Conduct risk assessments, deviation reviews, and CAPA evaluations from a validation perspective, ensuring robust GMP compliance.
• Provide validation expertise to support NPD/NPI projects, regulatory submissions, and cross‑functional change controls.
• Contribute to inspection readiness, continuous improvement initiatives, and the development of a modern validation culture, while leading and mentoring a small team.

The ideal candidate will have:

• Strong background in pharmaceutical manufacturing validation
• Degree in a Life Sciences or Engineering discipline (advantageous)
• Minimum of 3 years' hands‑on validation experience
• Proven expertise in ICH Q3D Elemental Impurities and PDE assessments
• Solid understanding of GMP and modern validation principles
• Experience supporting change controls, deviations, and continuous improvement
• Confident communicator able to influence across departments and manage competing priorities