Principal Scientist PKPD

CK Group- Science, Clinical and Technical; Slough; On-site; GBP 150,000 - 200,000; Full time

Job summary

A leading global biopharmaceutical company in Slough is seeking a Principal Scientist PKPD to develop non-clinical PKPD studies and lead the PKPD strategy. The ideal candidate will have over 5 years of experience in PKPD data analysis and a relevant degree. This role includes responsibilities such as protocol design and data reporting for regulatory submissions. Competitive hourly pay offered.

Qualifications

• 5+ years hands-on experience in PKPD data analysis.
• Experience in designing non-clinical study protocols.
• Record of publications relevant to PKPD.

Responsibilities

• Participate in the development of PKPD studies.
• Lead non-clinical PKPD strategy.
• Deliver PKPD study reports for regulatory submissions.

Skills

Non-clinical PKPD study design

Data analysis and interpretation

Proficiency in Phoenix-WinNonlin

Good written and verbal communication skills

Education

PhD/MSc/BSc in a relevant discipline

Tools

Phoenix-WinNonlin

Berkeley Madonna

R

Job description

Overview

CK Group are recruiting for a Principal Scientist PKPD to join a global pharmaceutical company on a contract basis initially for 12 months.

Salary: £35.20 Per hour (PAYE) / £47.92 (Umbrella) - flexible for experienced candidates.

Responsibilities

• Participate in the development of non-clinical PKPD and GLP toxicokinetics studies.
• Lead the non-clinical PKPD strategy.
• Participate in protocol designs and writing by providing scientific support and input into regulatory study designs and protocols.
• Work collaboratively with project team representatives (e.g., Non-Clinical Safety, Bioanalysis, Clinical Pharmacology) and with CROs to ensure high quality data is generated.
• Deliver PKPD study reports and integrated summaries of the studies and participate in regulatory submission documents.
• Facilitate the advancement of drug candidates by building a thorough knowledge of the drug pharmacology and PKPD.

Your Background

• Experience working in a matrix environment, to help design and set non-clinical PKPD study protocols, and analyze, interpret, and report PKPD results including GLP toxicokinetics studies.
• PhD/MSc/BSc in a relevant discipline (quantitative pharmacology; pharmacokinetics/pharmacodynamics; DMPK, etc.) with more than 5 years hands-on experience in PKPD data analysis within a pharma company or CRO environment.
• Good understanding of pharmacology and pharmacologic processes related to disease and drug mechanisms.
• Hands-on experience in delivering high quality pre-clinical PKPD data analysis. Proficiency in the use of Phoenix-WinNonlin for PKPD analysis is essential. Use of other modelling and simulation packages and tools, such as Berkeley Madonna and/or R, would be advantageous.
• Good written and verbal communication skills, and ability to communicate study results and produce high standard reports that meet regulatory submission standards. A record of publications and other external scientific contributions relevant to PKPD will be a plus.

Company

Our client is a global biopharmaceutical company focused on creating value for people living with severe diseases in immunology and neurology now and into the future.

Location

This role is based at our client's site in Slough.

Apply

For more information, or to apply for this Principal Scientist PKPD, please contact the Key Accounts Team on (phone number removed) or email (url removed). Please quote reference (Apply online only).

It is essential that applicants hold entitlement to work in the UK. Please note: This role may be subject to a satisfactory basic Disclosure and Barring Service (DBS) check.

INDKA