Postdoctoral Scientist - PNAC - Dr Joe Yeeles - LMB 2740

MRC Laboratory of Molecular Biology (LMB); Cambridge; On-site; GBP 43,000; Full time

Job summary

A prominent research institute in Cambridge is seeking a Postdoctoral Scientist to join their Protein and Nucleic Acid Chemistry Division. You will focus on the molecular mechanisms of chromosome replication in yeast and humans, working under a Wellcome Trust grant. Applicants should hold a PhD in a relevant area or be close to completion, with a strong background in biochemistry and genome integrity. This is a three-year training position that offers numerous benefits, including generous holiday entitlement and professional development opportunities.

Benefits

Defined benefit pension scheme

40.5 days holiday entitlement

Employee discount scheme

Training and development opportunities

Qualifications

• You will have a PhD in a relevant area, or be due to complete a PhD within 6 months.
• Strong background in in vitro biochemistry, genome integrity studies or cryo-EM is essential.
• Previous research experience on DNA replication is desirable but not essential.

Responsibilities

• Join the Yeeles group in the Protein and Nucleic Acid Chemistry Division.
• Work to understand molecular mechanisms of replisome assembly in yeast and human.
• Participate in a project supported by a Wellcome Trust grant.

Skills

in vitro biochemistry

genome integrity studies

cryo-EM

DNA replication

Education

PhD in a relevant area

Job description

Postdoctoral Scientist
Salary £42,694 per annum
MRC Laboratory of Molecular Biology, Cambridge, UK

Overview

We are looking for an enthusiastic and motivated person to join the Yeeles group in the Protein and Nucleic Acid Chemistry Division at LMB. You will join a friendly, supportive and ambitious lab focused on understanding at the molecular level how accurate and complete chromosome replication is accomplished by the replisome. The project will focus on the molecular mechanisms of replisome assembly in yeast and human and is supported by a Wellcome Trust grant.

Qualifications

You will have a PhD in a relevant area, or be due to complete a PhD within 6 months. A strong background in either in vitro biochemistry, genome integrity studies or cryo-EM is essential. Previous research experience on DNA replication is desirable but is not essential provided you are highly motivated to learn and share knowledge with the group.

Position Details

This is a three-year training and development position suitable for you if you have recently completed your doctoral studies, or you are looking to move into a new research discipline and/or need to further develop your research skills. Working with our world class scientists you will be working in an Institute renowned for its excellent scientific facilities and high-quality research.

Benefits

The LMB has a collaborative working culture and state-of-the‑art building based on the Cambridge Biomedical Campus. We have on‑site parking, cycle enclosures and excellent public transport links to the site. We have a staff restaurant with roof terrace and access to a Campus nursery and sports and social facilities. You will be eligible to join our defined benefit pension scheme, a holiday entitlement of 40.5 days (including bank holidays and privilege days) and a generous employee discount scheme. We are also committed to providing training and development opportunities including support towards role‑related qualifications. Further information about the benefits available can be found at http://www.discover.ukri.org/benefits-of-working-at-ukri.

Other Information

The LMB is a world‑class research institute within UK Research and Innovation (UKRI). UKRI is nine research councils, working together across all disciplines and sectors. More information can be found at www.ukri.org and www.mrc-lmb.cam.ac.uk.

This role qualifies for endorsement by UKRI for a UK Global Talent Visa, for which the successful applicant is likely to be eligible to apply. Immigration costs (visa and health surcharge) can be reclaimed from UKRI after taking up the post (terms and conditions apply).

Closing date: 15th December 2025

Final appointments will be subject to a pre‑employment screening.

We actively support equality, diversity and inclusion in all our activities, processes and culture. We encourage applications from all sections of society. The LMB particularly welcomes women, minority ethnic and disabled candidates to apply for this vacancy as they are currently under‑represented. We are a disability inclusive employer and encourage disabled people to apply for this role. You are very welcome to contact us for information about the application process and any adjustments you may require; [e-mail].