Clinical Operations Manager

Mantell Associates; Remote; GBP 80,000 - 100,000; Full time

Job summary

A forward-looking Biotech company is seeking a motivated Clinical Operations Manager to oversee clinical trials from start to finish. This fully remote UK role involves leading operational aspects, ensuring compliance with regulations, and managing vendor relationships. The ideal candidate should have 4-7 years of clinical operations experience in biotech, exceptional communication skills, and a proven ability to manage multiple projects effectively.

Qualifications

• Minimum of 4-7 years’ experience in clinical operations or related roles within biotech, pharma, or CRO settings.
• Strong knowledge of ICH-GCP and clinical trial regulations (UK / EU).
• Demonstrated ability to manage multiple trials or projects in parallel.

Responsibilities

• Lead operational aspects of clinical trials from start-up through close-out, ensuring timely delivery.
• Coordinate site selection, feasibility assessments, and vendor management.
• Monitor trial progress, manage timelines, budgets, and resources.

Skills

Clinical trial management

Stakeholder management

Regulatory requirements knowledge

Problem-solving skills

Job description

Mantell Associates is partnered with a forward-looking Biotech company, who is seeking a motivated and experienced Clinical Operations Manager to join their clinical development team on a contract basis. This fully remote UK-based role offers flexibility while playing a critical part in the execution and management of clinical trials that support breakthrough therapies.

Clinical Operations Manager - Responsibilities

• Lead and manage operational aspects of clinical trials from study start-up through close-out, ensuring timely delivery of milestones and adherence to regulatory and quality standards
• Coordinate site selection, feasibility assessments, site initiation, vendor management, and contracts, ensuring alignment with study protocols and timelines
• Oversee patient recruitment strategies, enrollment tracking, retention and retention-related logistics to meet study enrolment targets
• Monitor trial progress, manage timelines, budgets, and resources; work closely with Clinical Operations, Data Management, Safety / Pharmacovigilance, and Regulatory teams to ensure smooth execution
• Ensure compliance with ICH-GCP, national and international regulations, and company SOPs; maintain high standards of data integrity and patient safety
• Provide regular status reports, risk assessments, and contingency plans to senior leadership and stakeholders; proactively identify and manage operational risks
• Support vendor and CRO oversight, including performance monitoring, quality assurance, and deliverable tracking
• Facilitate cross-functional communication among clinical, regulatory, safety, and project teams to ensure coordinated execution and alignment of trial objectives
• Implement continuous process improvements - optimising workflows, documentation, and trial management procedures to boost efficiency and quality.

Clinical Operations Manager - Requirements

• Minimum of 4-7 years’ experience in clinical operations or related roles within biotech, pharma, or CRO settings, with direct involvement in clinical trial management
• Strong knowledge of ICH-GCP, clinical trial regulations (UK / EU), and regulatory requirements; experience working with multinational and remote trial teams is a plus
• Demonstrated ability to manage multiple trials or projects in parallel, with solid skills in planning, coordination, and problem-solving under tight timelines
• Excellent communication and stakeholder-management skills; comfortable interacting across cross-functional teams and external partners
• Proven record in site management, vendor or CRO oversight, and patient recruitment / retention strategies
• Ability to work independently and remotely, with self-motivation, discipline, and ability to drive projects to completion
• Based in the UK, with eligibility to work full time and ability to commit to contract duration

Mantell Associates is a specialist Pharmaceutical and Life Science headhunting firm. For more information on this opportunity, contact us at [phone].