Executive Director, Rare Kidney Disease Clinical Development

Travere Therapeutics; Kansas City (MO); Hybride; USD 246 000 - 332 000; Plein temps

Résumé du poste

Travere Therapeutics is seeking an Executive Director, Clinical Development to lead nephrology development programs. You will shape development strategy, collaborate with Research, Regulatory, Biostatistics, Medical Affairs, and Commercial teams, and drive cross-functional governance across trials in rare kidney diseases.

Reporting to Global Clinical Development leadership, you will ensure scientifically rigorous, patient-centered, and operationally feasible plans, partnering with

Qualifications

• MD, DO, or equivalent medical degree required; advanced training in nephrology strongly preferred.
• 10+ years of relevant experience in clinical research or drug development required, including at least 5 years in a leadership role responsible for clinical development strategy and major program decisions.
• Prior experience leading clinical programs in nephrology, rare disease, or closely related therapeutic areas strongly preferred.
• Strong understanding of clinical trial design, dose selection, safety assessment, endpoint strategy, and interpretation of complex clinical datasets.
• Experience with regulatory submissions and health authority interactions.
• Deep appreciation for the unique challenges of rare disease development, including small populations, site selection, natural history, endpoint selection, and patient engagement.
• Excellent communication and influence skills, with the ability to synthesize complex issues for senior leaders and governance bodies.

Responsabilités

• Lead the overall clinical development strategy for assigned clinical trial(s) as a key contributor to indication strategy, target product profile, clinical positioning, and lifecycle planning.
• Design and oversee clinical studies across phases, including protocol concept, eligibility criteria, endpoints, dose selection, and statistical considerations.
• Provide leadership for study conduct, including protocol deviation review and data interpretation.
• Lead analysis and interpretation of clinical data and author or review key documents including protocols, IBs, CSRs, abstracts, manuscripts, and health authority briefing materials.
• Partner with Biometrics to define analysis strategy and ensure clinically meaningful interpretation of efficacy, safety, PK/PD, and biomarker data.

Connaissances

Leadership

Regulatory knowledge

Clinical trial design

Nephrology experience

Cross-functional collaboration

Regulatory submissions

Data interpretation

Stakeholder management

Communication skills

Travel availability

Formation

MD/DO or equivalent medical degree

Description du poste

Travere Therapeutics is seeking an Executive Director, Clinical Development to lead nephrology development programs. You will shape development strategy, collaborate with Research, Regulatory, Biostatistics, Medical Affairs, and Commercial teams, and drive cross-functional governance across trials in rare kidney diseases.

Reporting to Global Clinical Development leadership, you will ensure scientifically rigorous, patient-centered, and operationally feasible plans, partnering with