Remote Executive Director, Rare Kidney Disease Development

Travere Therapeutics; New York (NY); On-site; USD 246,000 - 332,000; Full time

Benefits offered by this job

Premium health

Retirement plans with employer match

Generous paid time off

Job summary

Travere Therapeutics is seeking an experienced Executive Director, Clinical Development to lead nephrology programs within rare kidney diseases. This role partners across Research, Regulatory, Biometrics, Medical Affairs, and Commercial to shape development strategy and ensure scientifically rigorous, patient-centered plans.

Reporting to the VP of Global Clinical Development, you will drive program strategy, governance, and lifecycle decisions while guiding study design, data interpretation, and

Qualifications

• MD, DO, or equivalent medical degree required; advanced training in nephrology strongly preferred.
• 10+ years of relevant experience in clinical research or drug development required, including at least 5 years in a leadership role responsible for clinical development strategy and major program decisions.
• Prior experience leading clinical programs in nephrology, rare disease, or closely related therapeutic areas strongly preferred.
• Strong understanding of clinical trial design, dose selection, safety assessment, endpoint strategy, and interpretation of complex clinical datasets.

Responsibilities

• Lead the overall clinical development strategy for assigned clinical trial(s) as a key contributor to indication strategy, target product profile, clinical positioning, and lifecycle planning.
• Design and oversee clinical studies across phases, including protocol concept, eligibility criteria, endpoints, dose selection, and statistical considerations.
• Provide leadership for study conduct, including protocol deviation review and data interpretation.
• Lead analysis and interpretation of clinical data and author or review key documents including protocols, IBs, CSRs, abstracts, manuscripts, and health authority briefing materials.
• Partner with Biometrics to define analysis strategy and ensure clinically meaningful interpretation of efficacy, safety, PK/PD, and biomarker data.

Skills

Leadership in clinical development

Regulatory strategy experience

Experience in nephrology/rare diseases

Excellent communication skills

Education

MD/DO or equivalent

Advanced nephrology training (preferred)

Job description

Travere Therapeutics is seeking an experienced Executive Director, Clinical Development to lead nephrology programs within rare kidney diseases. This role partners across Research, Regulatory, Biometrics, Medical Affairs, and Commercial to shape development strategy and ensure scientifically rigorous, patient-centered plans.

Reporting to the VP of Global Clinical Development, you will drive program strategy, governance, and lifecycle decisions while guiding study design, data interpretation, and