Staff Engineer, Systems Design – Platform Engineering

ThermoFisher Scientific; Singapore; On-site; SGD 80,000 - 110,000; Full time

Job summary

A leading biotechnology firm is seeking a Staff Systems Engineer for their Platform R&D team in Singapore. The role involves integrating hardware, software, and algorithms into genetic analysis systems while collaborating across various functions. Candidates should possess extensive experience in system integration, risk analysis, and a degree in Engineering or Applied Physics. This position offers opportunities to innovate and impact the development of next-generation instruments.

Qualifications

• 10+ years of relevant industry experience or 5–7 years with a Master’s/Ph.D.
• Proven track record in completing system integration and verification.
• Experience in regulated environments (ISO 13485, FDA QSR).

Responsibilities

• Translate requirements into system specifications.
• Lead system integration efforts for genetic analyzer instrumentation.
• Develop and validate new methods to improve efficiency.

Skills

System integration

Verification testing

Statistical methods

Risk analysis

Communication

Education

Bachelor’s degree in Engineering or Applied Physics

Master’s/Ph.D. in relevant field

Tools

MATLAB

LabVIEW

Python

SolidWorks

Job description

Work Schedule

Standard (Mon-Fri)

Environmental Conditions

Office

Job Description

Job Title: Staff Engineer, Systems Design – Platform Engineering

Location: Singapore R&D

Business Unit: Genetic Sciences Division – qPCR/dPCR or MA Platforms

How You'll Make an Impact

As a Staff Systems Engineer in our Platform R&D team, you will play an important role in developing next-generation genetic analysis instrumentation. This is a hands‑on role where you will integrate hardware, software, assays, and algorithms into systems that provide accuracy, and reliability for customers worldwide! You will partner across fields — from molecular biology to embedded systems — to translate user and business needs into innovative system builds.

What You Will Do

System Definition and Architecture

• Translate customer and product requirements into clear system‑level specifications and performance targets.
• Develop system models and architecture frameworks spanning hardware, software, optics, and assay integration.
• Conduct system analyses, trade‑off studies, and feasibility assessments to inform build decisions.

Build and Integration

• Lead system integration efforts for prototype and production genetic analyzer instrumentation.
• Collaborate with electrical, mechanical, software, and assay teams to ensure robust subsystem interactions and signal integrity.
• Perform verification testing, root‑cause analysis, and system performance optimization.
• Apply modeling and data‑driven techniques (e.g., simulation, DOE, FMEA, RCA or equivalent experience) to evaluate and mitigate risks.

Innovation and Execution

• Develop and validate new methods and architectures to improve efficiency, precision, and reliability.
• Support early‑stage prototyping, technology down‑selection, and system scalability analysis.
• Drive adoption of systems engineering standard methodologies, including model‑based approaches and quantitative verification.

Collaboration Across Functions

• Work closely with Product Management, Manufacturing, Quality, and Service to ensure system builds meet functional, operational, and regulatory needs.
• Bring technical expertise during build reviews, risk assessments, and design transfers to manufacturing.

How You’ll Get Here

Education & Experience

• Bachelor’s degree or equivalent experience in Engineering (Mechanical, Electrical, Systems, or Software) or Applied Physics with 10+ years of relevant industry experience; or
• Master’s/Ph.D. with 5–7 years of experience developing life science instrumentation or diagnostic systems.

Technical Expertise

• Proven track record in completing system integration and verification for complex electro‑mechanical or optical instruments.
• Familiarity with thermal control, optics, detection systems, statistical methods, fluidics, and signal processing in PCR or similar analytical systems.
• Strong background in systems engineering methods: requirements management, modeling, FMEA, DOE, risk analysis, and reliability engineering.
• Skilled in tools such as MATLAB, LabVIEW, Python, SolidWorks, and simulation/modeling environments.
• Experience working in regulated environments (ISO 13485, FDA QSR, CE‑IVD) preferred.

Interpersonal & Leadership Attributes

• Self‑directed engineer with a balance of analytical depth and practical execution.
• Effective communicator across fields; able to synthesize complex findings for technical and non‑technical audiences.
• Thrives in multi‑functional, global R&D environments; capable of influencing outcomes through technical credibility.

Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.