Postdoctoral position in membrane protein structural biology M/F

CNRS; France; Sur place; EUR 20 000 - 40 000; Plein temps

Résumé du poste

A national research organization in France is seeking a motivated researcher with a Ph.D. to join a project focusing on the structure determination of proteins involved in T2 secretion systems. The role involves developing methods for protein production, optimizing cryoEM grids, and utilizing image processing for 3D reconstructions. Candidates should have a strong background in biochemistry and biophysics, with experience in electron microscopy being essential. This is a two-year full-time temporary position based in Bordeaux.

Qualifications

• Experience in biochemistry and membrane reconstitution is essential.
• Familiarity with membrane protein expression and purification is preferred.
• Ability to take initiatives and responsibility.

Responsabilités

• Work on structure determination of T2 secretion system partners.
• Develop methods for protein production and stabilization.
• Optimize cryoEM grids and process images for 3D reconstruction.

Connaissances

Biochemical techniques

Electron microscopy

Protein expression

Formation

Ph.D. degree in biochemistry or biophysics

Description du poste

Organisation/Company CNRS Department Chimie et Biologie des Membranes et des Nanoobjets Research Field Chemistry » Biochemistry Physics » Biophysics Biological sciences » Biological engineering Researcher Profile First Stage Researcher (R1) Country France Application Deadline 19 Dec 2025 - 23:59 (UTC) Type of Contract Temporary Job Status Full-time Hours Per Week 35 Offer Starting Date 16 Feb 2026 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

In the frame of granted ANR (French National Research Agency) project the candidate would work on the structure determination of partners of T2 secretion system using single particle cryoEM. He will develop method for protein production, for stabilizing these proteins, for optimizing cryoem grids, collect high resolution data and use image processing software to determine 3D reconstruction.
The project is within the framework of an ANR research program and will be conducted in collaboration with the groups of Romé Voulhoux (LBM, Marseille).

The successful candidate will join our group at the institute of Chimie et Biology des Membranes et Nano-objets (Pessac, Bordeaux) which aims at deciphering the molecular mechanisms of active transport across biological membranes, using biochemical, biophysical and cryoEM approaches.

The position is for 2 years and will be filled as soon as possible. The applicant should not have more than 2 years of experience after having completed his/her PhD. The salary will follow the CNRS guidelines.
The position is in a sector covered by the protection of scientific and technical potential (PPST) scheme and therefore, in accordance with regulations, requires your arrival to be authorised by the competent authority at the MESR

Research Field Biological sciences » Biological engineering Years of Research Experience None

Additional Information

Eligibility criteria

We are looking for a motivated and ambitious individual with a Ph.D. degree in biochemistry or biophysics. Experience in biochemistry and Membrane reconstitution, electron microscopy is essential; experience with membrane protein expression, and purification is preferred. Applicants should be able to take initiatives and responsibility within the work environment