PostDoc in Precision Immunotherapy / Antibody Engineering (m/w/d)

LMU Klinikum München; München; Presencial; EUR 55.000 - 70.000; Jornada completa

Ventajas ofrecidas por este puesto de trabajo

Job ticket

Company pension scheme

Discounts

Childcare services

Staff accommodation (if available)

Mobile work (if suitable)

Descripción de la vacante

LMU Klinikum München seeks a PostDoc in Precision Immunotherapy / Antibody Engineering to join Prof. Klein's translational program at LMU's CCRC & Gene Center.

The role covers engineering, production, purification of antibody formats, and optimization of assays, with leadership opportunities within an interdisciplinary, international team. The position is funded for two years and offers an international research environment, collaboration with academic and industrial partners, and a focus on

Formación

• PhD in biology, biochemistry, biotechnology, or equivalent.
• Solid experience in antibody engineering, protein expression and purification (FPLC).
• Molecular biology and cell biology techniques.
• iPSC cultivation or differentiation into immune cell types.
• Experience with in vitro or in vivo functional assays and multi-omics data analysis is advantageous.
• Ability to work independently in an interdisciplinary international team.
• Structured, meticulous and solution-oriented working style.
• Excellent English skills; German skills are an advantage.

Responsabilidades

• Engineer, produce and purify recombinant antibody formats.
• Set up and optimize in vitro and in vivo functional assays.
• Develop our iPSC-derived organoid system for patient-specific therapy testing.
• Plan and coordinate ongoing experiments and prepare data for publication and grants.
• Support the scientific supervision of junior researchers.

Conocimientos

Antibody engineering

Molecular biology

Cell biology

iPSC cultivation

In vitro/in vivo assays

Independent working

English proficiency

Educación

PhD in Biology/Biochemistry/Biotechnology or equivalent

Herramientas

FPLC

Descripción del empleo

PostDoc in Precision Immunotherapy / Antibody Engineering

(m/f/d)

Workplace

Campus Innenstadt

Working hours

Full time

Institution

Kinderklinik und Kinderpoliklinik im Dr. von Haunerschen Kinderspital

Department

Research - Klein Lab at the CCRC & Gene Center LMU

Date of entry

At the earliest possible date

Application deadline

Swift

Reference Number

2026-K-0416

The Hospital of the University of Munich, Germany, is one of the largest and most competitive university hospitals in Germany and Europe. 48 specialized hospitals, departments and institutions harbouring excellent research and education provide patient care at the highest medical level with around 12.000 employees.

Scope of duties

As a PostDoc in the research group of Prof. Christoph Klein, you will join a translational research program and with the option to take on a leadership role. You will be involved in a precision immunotherapy program based on an innovative conditional strategy (“AND-GATE”) to target cancer and immune cells. This includes the engineering, production and purification of novel recombinant antibody formats, the setup and optimization of in vitro and in vivo functional assays, and the further development of our iPSC-derived organoid system for patient-specific therapy testing. You will help plan and coordinate ongoing experiments, prepare scientific data for publication and grant applications, and support the scientific supervision of junior researchers.

Our requirements

• Completed PhD in Biology, Biochemistry, Biotechnology or a comparable field
• Solid experience in the following areas:
• Antibody engineering, protein expression and purification (e.g., FPLC)
• Molecular biology and cell biology techniques
• iPSC cultivation and/or differentiation into immune cell types
• Experience with in vitro or in vivo functional assays and multi-omics data analysis is an advantage
• The ability to work independently, as well as in an interdisciplinary and international team
• A structured, meticulous and solution-oriented working style
• Excellent English skills; German skills are an advantage

Our offer

• The position is initially funded for two years . Subject to a positive scientific re-evaluation, an extension is possible
• An innovative and challenging position within the research group of Prof. Christoph Klein, operating at the interface of translational immunotherapy, stem cell biology and precision medicine.
• An international and interdisciplinary research environment, supported by close collaboration with academic and industrial partners within an established research network
• Close collaboration with basic scientists, bioinformaticians and clinician scientists on two complementary translational projects
• A collaborative, supportive and inspiring working environment that encourages scientific independence
• Employment according to the German public-sector collective agreement (TV-L), including annual leave and additional benefits in accordance with the applicable regulations

Offers and services of the employer

• Further education and training
• Job ticket
• Company pension scheme
• Discounts
• Childcare services
• Staff accommodation (if available)
• Mobile work (if suitable)

Mr. Dr. Nickels, Philipp

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