Postdoc in Drug Discovery / Neutrophil-driven Inflammation (m/f/d)

LMU Klinikum München; München; On-site; EUR 43,000 - 64,000; Full time

Job summary

LMU Klinikum München invites applications for a Postdoc in Drug Discovery in the CCRC & Gene Center LMU, starting at the next possible date, full-time. You will join Prof.

Christoph Klein's translational program focusing on neutrophil-driven inflammation and have opportunities to take on leadership roles in a dynamic, internationally oriented team. You will differentiate iPSC-derived neutrophils, establish screening assays, and perform multi-omics profiling in collaboration with academic and

Qualifications

• PhD in biology, biochemistry, biotechnology, pharmacology or related field required.
• Experience with molecular/cellular biology techniques and iPSC work.
• Experience with screening assays and data analysis is essential.
• Strong ability to collaborate in interdisciplinary, international teams.

Responsibilities

• Join a translational research program on neutrophil-driven inflammation.
• Differentiate and characterize iPSC-derived neutrophils.
• Establish and run biochemical and cellular screening assays.
• Perform multi-omics profiling in collaboration with partners.
• Plan and coordinate experiments; prepare data for publication and grants; supervise junior researchers.

Skills

PhD in biology/biochem

iPSC culture/differentiation

Molecular biology techniques

High-throughput screening

Multi-omics analysis

English proficiency

Education

PhD in life sciences

Job description

The Hospital of the University of Munich, Germany, is one of the largest and most competitive university hospitals in Germany and Europe. 48 specialized hospitals, departments and institutions harbouring excellent research and education provide patient care at the highest medical level with around 12,000 employees.

The Kinderklinik und Kinderpoliklinik im Dr. von Haunerschen Kinderspital at the Campus Innenstadt invites applications for the Research – Klein Lab at the CCRC & Gene Center LMU, starting at the next possible date, full-time, for a

Postdoc in Drug Discovery / Neutrophil-driven Inflammation (m/f/d)

Scope of duties

As a Postdoc in the research group of Prof. Christoph Klein, you will join a translational research program with the option to take on a leadership role.

You will be involved in a first-in-class drug discovery project aimed at selectively modulating neutrophil-driven inflammation. Your work will cover the differentiation and functional characterization of iPSC-derived neutrophils, the establishment and execution of biochemical and cellular screening assays, as well as multi-omics profiling (transcriptomics, proteomics, metabolomics) in collaboration with our academic and industrial partners.

You will help plan and coordinate ongoing experiments, prepare scientific data for publication and grant applications, and support the scientific supervision of junior researchers.

Our requirements

• Completed PhD in Biology, Biochemistry, Biotechnology, Pharmacology or a comparable field
• Solid experience in the following areas:
  
  • Molecular biology and cell biology techniques
  • iPSC cultivation and/or differentiation into immune cell types
  • Establishment and execution of biochemical, cellular or high-throughput screening assays
• Experience with in vitro or in vivo functional assays and multi-omics data analysis is an advantage
• The ability to work independently, as well as in an interdisciplinary and international team
• A structured, meticulous and solution-oriented working style
• Excellent English skills; German skills are an advantage

Our offer

• An innovative and challenging position within the research group of Prof. Christoph Klein, operating at the interface of translational immunotherapy, stem cell biology and precision medicine
• An international and interdisciplinary research environment, supported by close collaboration with academic and industrial partners within an established research network
• Close collaboration with basic scientists, bioinformaticians and clinician scientists on two complementary translational projects
• A collaborative, supportive and inspiring working environment that encourages scientific independence
• Employment according to the German public-sector collective agreement (TV-L), including annual leave and additional benefits in accordance with the applicable regulations
• Further education and training, a company pension scheme, childcare services, mobile work (if suitable), a job ticket, discounts and staff accommodation (if available)

The position is initially funded for two years. Subject to a positive scientific re-evaluation, an extension is possible.

Contact

Disabled persons will be preferentially considered in case of equal qualification. Presentation costs cannot be refunded. For further information please contact Dr. Philipp Nickels, phone [phone] - 57109.