Postdoctoral Fellow (PhD/Dr. rer. nat., m/f/div., E13 TV-L 100%) (m/w/div.)

Deutsches Diabetes-Zentrum; Düsseldorf; On-site; EUR 55,000 - 65,000; Full time

Job summary

Das Deutsche Diabetes-Zentrum (DDZ) in Düsseldorf sucht eine/n Postdoctoral Fellow (PhD/Dr. rer. nat., m/f/div., E13 TV-L 100%). Das Team forscht am ERC Starting Grant MYOSCAN zur intertissualen Kommunikation und Muskelsecretomforschung.

Aufgaben umfassen eigenständige Experimente, Publikationen in internationalen Fachzeitschriften und Mentoring junger Wissenschaftler. Die Anstellung beginnt ab dem 01.03.2027 oder später; Vertrag 2 Jahre, Verlängerung möglich.

Qualifications

• PhD in molekularbiologie, Zellbiologie, Biochemie, Physiologie, Bewegungswissenschaft, Metabolismus, Krebsbiologie oder verwandtem Bereich.
• Starke Expertise in mindestens einem der folgenden Bereiche: Proteomics/Mass Spectrometry, Secretome-Analyse, Zellbiologie, Molekulare Signalingwege, metabolische Forschung oder Krebsbiologie.
• Erfahrung im Umgang mit Mausmodellen wünschenswert.
• Sehr gute Englischkenntnisse (Schrift/Text).
• Erfahrung in der Betreuung von Studierenden oder Doktorandinnen.

Responsibilities

• Eigenständige Durchführung von Projekten im ERC Starting Grant MYOSCAN.
• Analytische Auswertung von Daten und Veröffentlichungsergebnisse.
• Mentoring/junge Wissenschaftlerinnen innerhalb des Teams.

Skills

PhD in life sciences

Mouse models

Secretome analysis

English proficiency

Supervisory experience

Education

PhD in molekularbiologie oder verwandtem Feld

Tools

Proteomics

Mass spectrometry

Secretome analysis

Molecular signaling

Job description

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Institut für Klinische Biochemie und Pathobiochemie (Direktor: Univ.-Prof. Dr. rer. nat. Hadi Al-Hasani), Nachwuchsforschungsgruppe Crosstalk (Leiterin: Melanie Mittenbühler, Dr.)

The German Diabetes Center (DDZ), Leibniz Institute for Diabetes Research at the Heinrich Heine University (HHU) Düsseldorf is an interdisciplinary research institute that links basic and clinical sciences to improve prevention, diagnosis and therapy of Diabetes mellitus and its complications. The Junior Research Group Crosstalk (head: Dr. Melanie Mittenbühler) at the Institute for Clinical Biochemistry and Pathobiochemistry focuses on how inter-tissue communication impacts energy balance and metabolic health. We are seeking a talented and highly motivated

Postdoctoral Fellow (PhD/Dr. rer. nat., m/f/div., E13 TV-L 100%)

Ihr Aufgabengebiet umfasst

to join our research group. Our group investigates how skeletal muscle acts as an endocrine organ and communicates with other tissues through secreted signaling molecules, particularly myokines. In the ERC Starting Grant project MYOSCAN, we systematically investigate how exercise and age-related muscle loss alter the skeletal muscle secretome. We aim to identify novel exercise-sensitive myokines and define their roles in sarcopenia, metabolic disease, and cancer biology. A central question is whether muscle-derived factors promote or suppress tumor growth and how these signaling pathways can be therapeutically targeted.

Wir erwarten von Ihnen

• PhD in molecular biology, cell biology, biochemistry, physiology, exercise science, metabolism, cancer biology, or a related field
• Strong expertise in at least one of the following areas: proteomics/mass spectrometry, secretome analysis, cell biology, molecular signaling, metabolic research, or cancer biology. Experience in working with mouse models is preferred
• Scientific curiosity, initiative, strong analytical skills, and the ability to work both independently and collaboratively
• Excellent written and spoken English skills
• Experience in supervising students or doctoral researchers

Wir bieten Ihnen

We provide a fully funded postdoctoral position within an excellently supported ERC Starting Grant project, an exciting, dynamic and international working environment, and a structured and coherent mentoring and training program. You will be able to learn state-of-the-art methodologies in a team of young scientists. Initially, the position is to be awarded for 2 years starting from 01.03.2027 or later. An extension of the contract period is envisaged. The employment contract is governed by TV-L in its current version for North Rhine-Westphalia, including the special regulations regarding the scientific area. The salary is based on qualification and experience, according to TV-L.

Females are especially encouraged to apply, and in the case of equal qualification, handicapped persons will be given preference. The German Diabetes Center is committed to family-friendly working conditions and equal gender policy. Since May 2011, the DDZ is a “Career and Family” audit-acknowledged center. The provisions of

• 7 no. 1 of the Act on Part-Time Work and Fixed-Term Employment are taken into account.