Postdoc in Precision Immunotherapy / Antibody Engineering (m/f/d)

LMU Klinikum München; München; On-site; EUR 52,000 - 70,000; Full time

Job summary

LMU Klinikum München invites applications for a Postdoc in Precision Immunotherapy / Antibody Engineering. You join the Klein Lab at the CCRC & Gene Center LMU and contribute to a translational program targeting cancer and immune cells with innovative antibody formats.

You will plan experiments, optimize assays, and help prepare publications and grant applications while mentoring junior researchers. The role is initially funded for two years with potential extension.

Qualifications

• Completed PhD in Biology, Biochemistry, Biotechnology or a comparable field.
• Experience in antibody engineering, protein expression and purification (e.g., FPLC).
• Proficiency in molecular biology and cell biology techniques.
• Experience with iPSC cultivation and differentiation into immune cells.
• Ability to work independently and in interdisciplinary international teams.
• Excellent English skills; German skills are an advantage.

Responsibilities

• Plan and coordinate ongoing experiments in translational immunotherapy.
• Prepare scientific data for publication and grant applications.
• Support scientific supervision of junior researchers.
• Engage in leadership within the research group as needed.
• Collaborate with collaborators across basic science and clinicians.

Skills

Antibody engineering

Protein expression & purification

Molecular biology techniques

Cell biology techniques

iPSC cultivation & differentiation

Independent interdisciplinary work

English proficiency

Education

PhD in Biology/Biochemistry/Biotechnology or comparable field

Tools

FPLC

Job description

The Hospital of the University of Munich, Germany, is one of the largest and most competitive university hospitals in Germany and Europe. 48 specialized hospitals, departments and institutions harbouring excellent research and education provide patient care at the highest medical level with around 12,000 employees.

The Kinderklinik und Kinderpoliklinik im Dr. von Haunerschen Kinderspital at the Campus Innenstadt invites applications for the Research – Klein Lab at the CCRC & Gene Center LMU, starting at the next possible date, full-time, for a

Postdoc in Precision Immunotherapy / Antibody Engineering (m/f/d)

Scope of duties

As a Postdoc in the research group of Prof. Christoph Klein, you will join a translational research program with the option to take on a leadership role.

You will be involved in a precision immunotherapy program based on an innovative conditional strategy ("ANDGATE") to target cancer and immune cells. This includes the engineering, production and purification of novel recombinant antibody formats, the setup and optimization of in vitro and in vivo functional assays, and the further development of our iPSC-derived organoid system for patient-specific therapy testing.

You will help plan and coordinate ongoing experiments, prepare scientific data for publication and grant applications, and support the scientific supervision of junior researchers.

Our requirements

• Completed PhD in Biology, Biochemistry, Biotechnology or a comparable field
• Solid experience in the following areas:
  
  • Antibody engineering, protein expression and purification (e.g., FPLC)
  • Molecular biology and cell biology techniques
  • iPSC cultivation and/or differentiation into immune cell types
• Experience with in vitro or in vivo functional assays and multi-omics data analysis is an advantage
• The ability to work independently, as well as in an interdisciplinary and international team
• A structured, meticulous and solution-oriented working style
• Excellent English skills; German skills are an advantage

Our offer

• An innovative and challenging position within the research group of Prof. Christoph Klein, operating at the interface of translational immunotherapy, stem cell biology and precision medicine
• An international and interdisciplinary research environment, supported by close collaboration with academic and industrial partners within an established research network
• Close collaboration with basic scientists, bioinformaticians and clinician scientists on two complementary translational projects
• A collaborative, supportive and inspiring working environment that encourages scientific independence
• Employment according to the German public-sector collective agreement (TV-L), including annual leave and additional benefits in accordance with the applicable regulations
• Further education and training, a company pension scheme, childcare services, mobile work (if suitable), a job ticket, discounts and staff accommodation (if available)

The position is initially funded for two years. Subject to a positive scientific re-evaluation, an extension is possible.

Disabled persons will be preferentially considered in case of equal qualification. Presentation costs cannot be refunded.