PostDoc in Drug Discovery / Neutrophil-driven Inflammation (m/w/d)

Lmu Klinikum; München; Híbrido; EUR 52.000 - 65.000; Jornada completa

Descripción de la vacante

LMU Klinikum's Klein Lab at the CCRC & Gene Center LMU invites applications for a PostDoc in Drug Discovery focused on neutrophil-driven inflammation. The project includes iPSC-derived neutrophils, biochemical and cellular assays, and multi-omics profiling in collaboration with partners.

The candidate should have a PhD in biology or related fields and strong English; German is a plus. The two-year position may be extended pending scientific evaluation.

Formación

• PhD in biology, biochemistry, biotechnology, pharmacology or a comparable field.
• Solid experience in molecular biology and cell biology techniques.
• Experience with iPSC cultivation and/or differentiation into immune cell types.
• Experience establishing and executing biochemical or cellular screening assays.
• Multi-omics data analysis is advantageous.
• Ability to work independently and in an international, interdisciplinary team.
• Excellent English; German skills are a plus.

Responsabilidades

• Join a translational research program and potentially take a leadership role.
• Work on a first-in-class drug discovery project targeting neutrophil-driven inflammation.
• Differentiate and characterize iPSC-derived neutrophils and develop screening assays.
• Perform multi-omics profiling and collaborate with academic and industrial partners.
• Coordinate ongoing experiments and contribute to publications and grant proposals.
• Support supervision of junior researchers.

Conocimientos

Molecular biology

Cell biology

iPSC work

High-throughput assays

Multi-omics data

Biochemical assays

Data analysis

Educación

PhD in Biology/related field

Herramientas

iPSC differentiation

Descripción del empleo

PostDoc in Drug Discovery / Neutrophil-driven Inflammation

(m/f/d)

Workplace

Working hours

Full time

Institution

Department

Research - Klein Lab at the CCRC & Gene Center LMU

Date of entry

At the earliest possible date

Swift

Reference Number

The Hospital of the University of Munich, Germany, is one of the largest and most competitive university hospitals in Germany and Europe. 48 specialized hospitals, departments and institutions harbouring excellent research and education provide patient care at the highest medical level with around 12.000 employees.

Scope of duties

As a PostDoc in the research group of Prof. Christoph Klein, you will join a translational research program with the option to take on a leadership role.

You will be involved in a first-in-class drug discovery project aimed at selectively modulating neutrophil-driven inflammation. Your work will cover the differentiation and functional characterization of iPSC-derived neutrophils, the establishment and execution of biochemical and cellular screening assays, as well as multi-omics profiling (transcriptomics, proteomics, metabolomics) in collaboration with our academic and industrial partners.

You will help plan and coordinate ongoing experiments, prepare scientific data for publication and grant applications, and support the scientific supervision of junior researchers.

Our requirements

Completed PhD in Biology, Biochemistry, Biotechnology, Pharmacology or a comparable field

• Solid experience in the following areas:


• Molecular biology and cell biology techniques


• iPSC cultivation and/or differentiation into immune cell types


• Establishment and execution of biochemical, cellular or high-throughput screening assays


• Experience with in vitro or in vivo functional assays and multi-omics data analysis is an advantage


• The ability to work independently, as well as in an interdisciplinary and international team


• A structured, meticulous and solution-oriented working style


• Excellent English skills; German skills are an advantage

Our offer

The position is initially funded for two years . Subject to a positive scientific re-evaluation, an extension is possible

• An innovative and challenging position within the research group of Prof. Christoph Klein, operating at the interface of translational immunotherapy, stem cell biology and precision medicine.


• An international and interdisciplinary research environment, supported by close collaboration with academic and industrial partners within an established research network


• Close collaboration with basic scientists, bioinformaticians and clinician scientists on two complementary translational projects


• A collaborative, supportive and inspiring working environment that encourages scientific independence


• Employment according to the German public-sector collective agreement (TV-L), including annual leave and additional benefits in accordance with the applicable regulations

Disabled persons will be preferentially considered in case of equal qualification. Presentation costs cannot be refunded.

Please note that we cannot reimburse travel expenses incurred through interviews.