Senior Scientist, High-Throughput Proteomics

BioSpace; Thousand Oaks (CA); On-site; USD 120,000 - 180,000; Full time

Benefits offered by this job

Retirement plan

Medical/dental/vision coverage

Discretionary annual bonus

Stock-based incentives

Paid time off

Job summary

Amgen in Thousand Oaks, CA seeks a Scientist in mass spectrometry-based proteomics to drive high-throughput workflows for target identification and drug discovery. You will contribute to both pipeline advancement and platform innovation, developing automated sample prep, data acquisition, and analysis across diverse assays.

The role requires hands-on expertise with high-throughput MS systems (Orbitrap-based), strong troubleshooting, and collaborative problem-solving within a cross-functional

Qualifications

• Doctorate or equivalent in a relevant field.
• Masters with 2 years related experience.
• Bachelors with 4 years related experience.

Responsibilities

• Design and implement high-throughput proteomics workflows.
• Perform automated sample prep and LC-MS/MS analyses.
• Collaborate as SME with biology, chemistry, and therapeutic areas.
• Analyze proteomics data to inform mechanism of action and target engagement.
• Maintain and troubleshoot mass spectrometry systems and workflows.
• Present findings to cross-functional teams with clear documentation.

Skills

Mass spectrometry

Proteomics

High-throughput workflows

LC-MS/MS

Data analysis

Education

PhD/MD/PharmD with relevant experience

MS with 2 years related experience

BS with 4 years related experience

Tools

Orbitrap platforms

LCMS/MS platforms

Automation platforms

Job description

Amgen in Thousand Oaks, CA seeks a Scientist in mass spectrometry-based proteomics to drive high-throughput workflows for target identification and drug discovery. You will contribute to both pipeline advancement and platform innovation, developing automated sample prep, data acquisition, and analysis across diverse assays.

The role requires hands-on expertise with high-throughput MS systems (Orbitrap-based), strong troubleshooting, and collaborative problem-solving within a cross-functional