Proteomics Scientist (Mass Spec) — Flexible Work Options

Amgen; Thousand Oaks (CA); Vor Ort; USD 115.000 - 156.000; Vollzeit

Benefits dieser Stelle

Competitive benefits

Total Rewards Plan

Flexible work options

Zusammenfassung

Amgen in Thousand Oaks, California, is seeking a Scientist or Senior Scientist in mass spectrometry–based proteomics to generate proteomic insights that support target identification, drug discovery, and screening technology development.

You will design and implement high-throughput proteomics workflows, perform automated sample preparation and LC–MS/MS analyses, and collaborate with biology and chemistry teams to accelerate the pipeline.

Qualifikationen

• Doctorate degree (PhD, PharmD, or MD) with relevant experience.
• OR Master’s degree with 2 years of directly related experience.
• OR Bachelor’s degree and 4 years of directly related experience.
• Preferred: Doctorate in proteomics, chemoproteomics, biochemistry, chemistry, analytical science, or related.
• Hands‑on experience developing, optimizing, and applying mass spectrometry–based proteomics assays and workflows.
• Experience operating and troubleshooting advanced LC–MS/MS platforms, such as Orbitrap‑based systems, and analyzing proteomics data.
• Experience with high‑throughput sample preparation, miniaturization, and laboratory automation platforms.
• Demonstrated ability to develop, refine, or scale assays, analytical methods, or proteomics platforms.
• Quantitative and computational experience analyzing complex, high‑dimensional proteomics datasets.
• Experience working in a biotechnology, pharmaceutical, or drug‑discovery research environment is preferred.
• Ability to work effectively in a highly integrated, collaborative team environment; strong organizational, verbal, and written communication skills; and a demonstrated commitment to generating reliable, reproducible results.

Aufgaben

• Design, develop, optimize, and implement high-throughput mass spectrometry–based proteomics workflows and screening platforms to accelerate drug discovery.
• Execute automated sample preparation and LC–MS/MS analyses across a broad range of high-throughput proteomics assays.
• Collaborate closely with therapeutic area, biology and chemistry teams as a technical and scientific subject‑matter expert, contributing to data‑driven decision‑making.
• Analyze and interpret proteomics data to generate insights into mechanism of action, target engagement, selectivity, and other key drug‑discovery questions.
• Operate, maintain, troubleshoot, and continuously improve high-throughput mass spectrometry systems and associated analytical workflows.
• Present research findings at internal and external meetings, and clearly communicate experimental plans, results, and analyses to cross‑functional teams.
• Maintain accurate, organized, and timely documentation of experiments, protocols, methods, and data analyses.

Kenntnisse

Mass spectrometry expertise

Proteomics

High-throughput workflows

Team collaboration

Troubleshooting

Ausbildung

PhD/MD/PharmD

Masters degree

Bachelor degree

Tools

Orbitrap LC-MS/MS

High-throughput automation

Jobbeschreibung

Amgen in Thousand Oaks, California, is seeking a Scientist or Senior Scientist in mass spectrometry–based proteomics to generate proteomic insights that support target identification, drug discovery, and screening technology development.

You will design and implement high-throughput proteomics workflows, perform automated sample preparation and LC–MS/MS analyses, and collaborate with biology and chemistry teams to accelerate the pipeline.