Senior Scientist, Process Development - MS Protein Characterization

Amgen

Thousand Oaks (CA)

On-site

USD 126,000 - 171,000

Full time

14 days+

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Job summary

Amgen in Thousand Oaks, CA is seeking a Process Development Senior Scientist to lead analytical and biochemical characterization for pre-clinical biotherapeutic protein development, including mass spectrometry and LC-MS workflows. You will develop methods to assess biochemical attributes of candidate drug products and support regulatory submissions.

The role requires extensive MS expertise, sample prep, and collaboration across teams.

Qualifications

  • Doctorate degree PhD OR PharmD OR MD [and relevant post-doc where applicable]
  • Ph.D. in analytical chemistry, biochemistry, pharmaceutical sciences, physical sciences, chemical engineering, or biological sciences.
  • Experience with mass spectrometry of proteins, peptides and glycans.
  • Experience with Thermo mass spectrometers, Agilent and Thermo HPLC systems and data acquisition software.

Responsibilities

  • Characterize candidate molecules to support protein primary structure and modifications.
  • Develop analytical methods for MS-based characterization of therapeutic proteins.
  • Generate technical documents and presentations; support regulatory submissions and patents.

Skills

Mass spectrometry
Protein characterization
Analytical method development
Biotherapeutics

Education

PhD in analytical chemistry or related
Master's degree in scientific field
Bachelor's degree in scientific field

Tools

Chromeleon
BioPharma Finder
Skyline
Byonic
Byos
Expressionist
Excel
Origin
Thermo MS instruments

Job description

Amgen in Thousand Oaks, CA is seeking a Process Development Senior Scientist to lead analytical and biochemical characterization for pre-clinical biotherapeutic protein development, including mass spectrometry and LC-MS workflows. You will develop methods to assess biochemical attributes of candidate drug products and support regulatory submissions.

The role requires extensive MS expertise, sample prep, and collaboration across teams.

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