Senior Principal LNP Process Engineer

Eli Lilly and Company; Boston (MA); On-site; USD 114,000 - 191,000; Full time

Benefits offered by this job

401(k) plan

Pension

Vacation benefits

Medical, dental, vision benefits

Flexible spending accounts

Life insurance

Well-being programs

Job summary

Verve is seeking an experienced LNP Process Development Engineer to join the Late Stage LNP Process Development team within Verve. This lab-facing role advances lipid nanoparticle processes, focusing on high‑pressure mixing and TFF, supporting Phase 3 lock and tech transfer.

The candidate will drive DoE studies, collaborate across functions, and draft regulatory documents while ensuring robust process characterization and batch readiness in a Boston, MA setting.

Qualifications

• Earned Bachelor’s degree in Chemical Engineering, Biomedical Engineering, Biotechnology, or equivalent.
• 6+ years of biotech/pharma experience in LNP formulation or process development.
• Hands-on with LNP unit operations (TFF, high‑pressure mixing, filtration, lipid solubilization).
• Experience using statistical software (preferably JMP) to analyze data.
• Strong communication and teamwork skills; able to handle ambiguity.

Responsibilities

• Perform DoE-type studies to identify CPPs and NORs/PARs for unit operations.
• Lead design and execution of process development studies for scale‑up and lock.
• Support tech transfers and batch readiness activities; contribute to investigations.
• Author process development/characterization reports and regulatory documents.
• Present findings to stakeholders and maintain updated lab notebooks.
• Troubleshoot equipment and support maintenance as needed.

Skills

Data analysis

Team collaboration

Oral & written communication

Prioritization

Problem solving

Education

Bachelor's degree in a relevant science

Master’s degree (preferred)

Tools

JMP

Job description

Verve is seeking an experienced LNP Process Development Engineer to join the Late Stage LNP Process Development team within Verve. This lab-facing role advances lipid nanoparticle processes, focusing on high‑pressure mixing and TFF, supporting Phase 3 lock and tech transfer.

The candidate will drive DoE studies, collaborate across functions, and draft regulatory documents while ensuring robust process characterization and batch readiness in a Boston, MA setting.