Senior Director, LNP Formulation & Process Innovation

Pioneering Medicines; Cambridge (MA); On-site; USD 213,000 - 281,000; Full time

Job summary

Mirai Bio in Cambridge, MA is seeking a Senior Director of Lipid Nanoparticle (LNP) Formulation & Process Development to lead the company's LNP formulation, process development, and small-scale production for partner and internal programs.

You will build and lead a high‑performing team, define development strategies, collaborate across Analytical Development, Translational Biology, Project Management, and other functions, and serve as a senior technical interface with clients to advance

Qualifications

• Ph.D. with 12+ years industry experience; MS with 14+; BS with 16+ years.
• Hands-on LNP formulation and process development experience.
• Deep understanding of LNP composition, formation, purification, characterization; relations between parameters and attributes.
• Ability to lead complex technical programs, interpret data, troubleshoot, and establish development strategies.
• Proven experience leading and developing scientific teams; managing multiple programs and resources.
• Strong written, verbal, presentation, and client-facing communication skills.

Responsibilities

• Lead LNP formulation, process development, and small-scale production for partner and internal programs.
• Establish technical strategy and best practices for LNP formulation, process development, characterization, and production across multiple payloads and applications.
• Provide senior technical leadership across programs, including development strategy, experimental planning, data review, risk mitigation, and technical recommendations.
• Serve as a senior technical interface with clients and partners; support proposals, project scopes, presentations, and business development activities.
• Oversee non-GMP production of LNP formulations for in vitro, in vivo, and preclinical studies.
• Drive technical troubleshooting, process optimization, technology transfer, and continuous improvement of LNP production for mRNA, siRNA, gene-editing components, and other nucleic acid payloads.
• Establish workflows, documentation, and operational practices that improve quality, reproducibility, efficiency, and scalability.
• Lead, mentor, and develop the LNP team while managing priorities, resources, capacity, and organizational growth.
• Collaborate cross-functionally to align LNP development and production with broader program and company objectives.

Skills

LNP formulation

Process development

Team leadership

Data analysis

Client-facing

Verbal communication

Education

PhD in Pharmaceutical Sciences, Chemical Engineering, Bioengineering, Chemistry, Biochemistry, or related field

MS with 14+ years

BS with 16+ years

Job description

Mirai Bio in Cambridge, MA is seeking a Senior Director of Lipid Nanoparticle (LNP) Formulation & Process Development to lead the company's LNP formulation, process development, and small-scale production for partner and internal programs.

You will build and lead a high‑performing team, define development strategies, collaborate across Analytical Development, Translational Biology, Project Management, and other functions, and serve as a senior technical interface with clients to advance