Engineer (0-3 years)

Binding Minds Inc. (Certified Disability Owned Business Enterprise); Boston (MA); On-site; USD 90,000 - 120,000; Full time

Job summary

Binding Minds Inc. in Boston is seeking an Engineer for Formulation Sciences focused on lipid nanoparticle (LNP) discovery and development for CRISPR-based gene editing therapies.

The role supports LNP process development, scale-up and characterization within a multidisciplinary, fast-paced team. The ideal candidate has a 2+ year industry background in related fields, experience with LNP formulations and analytical methods, and strong problem-solving abilities.

Qualifications

• Bachelor’s or Master’s degree in related field with 2+ years of industry experience.
• Experience with lipid nanoparticle formulations and analytical characterization methods (preferred).
• Strong problem-solving skills and innovative approach.
• Ability to work independently in dynamic interdisciplinary teams; collaboration with partners desirable.
• Organized, detail-oriented, proactive self-starter.
• Excellent written and verbal communication; literature search and computer software proficiency.
• GMP environment knowledge including TFF, sterile filtration, single-use tech and aseptic processing preferred.

Responsibilities

• Support design, manufacturing and characterization of lipid nanoparticles (LNPs) for screening CPPs and CMAs affecting CQAs.
• Design and execute DoEs to advance LNP technology and process development.
• Define equipment specs, draft procedures and operating parameters/ranges.
• Write protocols, perform experiments, analyze data, and summarize results in reports.
• Assist in ordering supplies, preparing reagents, and maintaining lab safety.
• Multi-task across projects and manage time to achieve results.
• Collaborate with cross-functional teams and perform other duties as assigned.

Skills

Problem solving

Independent work

Team collaboration

Communication

Education

Bachelor’s or Master’s in chemical engineering, bioengineering, chemistry, pharmaceutical sciences

Job description

Job Title - Formulation Science Engineer

Location: Boston, MA

Duration: 12+ Months

Responsibilities

• Support the design, manufacturing and characterization of lipid nanoparticles (LNPs) for screening critical process parameters (CPPs) and critical material attributes (CMAs) that impact critical quality attributes (CQAs).
• Support the design and execution of a wide range of experiments including DoEs to advance LNP technology and process development.
• Participate in defining equipment specification/selection, draft procedures and recommended operating parameters/ranges
• Write protocols, perform experiments, organize and analyze data, interpret results, record experiments in an electronic lab notebook, and summarize work in presentations and technical reports
• Assist in ordering supplies, making reagents, and maintaining a safe and high-performing laboratory
• Multi-task across several projects and manage time effectively to achieve results
• Collaborate with multiple cross-functional teams and execute other duties as assigned

Quals--

Engineer, Formulation Sciences

The Position

We are seeking an Engineer to join our Formulation Sciences team focused on lipid nanoparticle (LNP) discovery and development for Verve’s Client CRISPR-based gene editing therapies. The successful candidate will be responsible for supporting LNP process development, scale-up, and characterization working as part of a multidisciplinary fast-paced team environment. The ideal candidate will have some process development industry experience with a desire to contribute to a team focused on championing nanomedicinal products and developing manufacturing solutions based on strong scientific principles.

Skills & Qualifications

• Bachelor’s/Master’s degree in chemical engineering, bioengineering, chemistry, pharmaceutical sciences, or another related field with 2+ years of relevant industry experience.
• Experience with lipid nanoparticle formulations and analytical characterization methods (Preferred)
• Strong problem-solving skills, and creative/innovative approach in problem solving.
• Ability to work independently and in very dynamic interdisciplinary team environments. Proven record in working with partners/collaborators is desirable.
• Organized, detail-oriented, and innovative self-starter who continuously seeks to improve existing laboratory methods and processes.
• Effective verbal and written communication skills; proficiency in literature search and relevant computer software skills are required.
• Knowledge of practices and equipment used to run manufacturing processes in a GMP environment, including TFF, sterile filtration, single-use technology, and sterile/aseptic processing preferred.