Senior LNP Production Research Associate

Socket.dev; Cambridge (MA); On-site; USD 81,000 - 107,000; Full time

Job summary

Mirai Bio is seeking a Senior Research Associate, LNP Production to design, produce, and optimize lipid nanoparticle formulations for preclinical research. This hands-on role requires expertise in LNP formulation, scale-up, and collaboration across programs.

You will work across internal platforms and partner projects to advance delivery technologies for nucleic acid cargos, contributing to platform improvements and robust workflows in a fast-paced environment.

Qualifications

• BS or MS in chemical/biochemical engineering, pharmaceutical sciences, chemistry, biology, or a related field.
• Hands-on experience with lipid nanoparticle formulation and production.
• Experience with LNP processing techniques and equipment across multiple scales (mixers, pumping, TFF).
• Familiarity with analytical techniques to characterize LNPs (size, polydispersity, encapsulation, etc.).
• Ability to independently run experiments and troubleshoot technical challenges.

Responsibilities

• Design, formulate, produce, and characterize LNPs to support preclinical research for internal platform and external partnerships.
• Execute LNP production across a range of process scales, from small-scale formulation and process optimization through larger-scale production.
• Operate and develop processes using relevant LNP manufacturing and process-development equipment, including mixers, pumping systems, tangential flow filtration (TFF), and related technologies.
• Troubleshoot formulation and process challenges and contribute to the optimization and continuous improvement of LNP production processes.
• Collaborate closely with scientists and cross-functional teams to design experiments, interpret results, and advance program objectives.
• Support the development and implementation of robust, reproducible LNP production and characterization workflows.
• Maintain accurate and thorough documentation of experimental procedures, results, and conclusions in electronic laboratory notebooks.
• Analyze and communicate experimental results and present findings and recommendations to cross-functional teams.
• Contribute to a culture of scientific rigor, collaboration, continuous learning, and operational excellence.

Skills

lipid nanoparticle formulation

LNP production

experimental design

troubleshooting

communication skills

team collaboration

data interpretation

Education

BS in chemical/biochemical engineering

MS in biochemical engineering

Tools

LNP processing equipment

TFF systems

particle size analysis

Job description

Mirai Bio is seeking a Senior Research Associate, LNP Production to design, produce, and optimize lipid nanoparticle formulations for preclinical research. This hands-on role requires expertise in LNP formulation, scale-up, and collaboration across programs.

You will work across internal platforms and partner projects to advance delivery technologies for nucleic acid cargos, contributing to platform improvements and robust workflows in a fast-paced environment.