Senior LNP Production Scientist

Mirai Bio, Inc.; Cambridge (MA); On-site; USD 81,000 - 107,000; Full time

Benefits offered by this job

Healthcare coverage

Annual incentive program

Retirement benefits

Job summary

Mirai Bio, Inc. in Cambridge, MA is seeking a Senior Research Associate, LNP Production to design, produce, and optimize lipid nanoparticle formulations for preclinical lipid-based therapeutics.

The role requires hands-on experience with LNP formulation and production and collaboration across programs and partners. The successful candidate will contribute to the continuous improvement of Mirai Bio's delivery platform, working across scales and using pumps, mixers, and TFF to advance multiple

Qualifications

• BS or MS in chemical engineering, biochemical engineering, pharmaceutical sciences, chemistry, biology, or a related scientific discipline
• BS + 5 years of relevant industry or research experience
• MS + 3 years of relevant industry or research experience
• Hands‑on experience with lipid nanoparticle formulation and production
• Experience with LNP processing techniques and equipment across multiple scales, including mixers, pumping systems, TFF, and related unit operations
• Familiarity with common analytical techniques used to characterize LNPs, including measurements of particle size, polydispersity, encapsulation efficiency, and other relevant physicochemical attributes
• Demonstrated ability to independently execute experiments, troubleshoot technical challenges, interpret data, and drive projects forward
• Strong organizational, written, and verbal communication skills
• Collaborative and adaptable team player who is equally comfortable working independently and partnering across functions
• Ability to prioritize effectively and consistently deliver high-quality results in a fast‑paced, dynamic environment

Responsibilities

• Design, formulate, produce, and characterize LNPs to support preclinical research for internal platform and external partnerships.
• Execute LNP production across a range of process scales, from small-scale formulation and process optimization through larger-scale production.
• Operate and develop processes using relevant LNP manufacturing and process-development equipment, including mixers, pumping systems, tangential flow filtration (TFF), and related technologies.
• Troubleshoot formulation and process challenges and contribute to the optimization and continuous improvement of LNP production processes.
• Collaborate closely with scientists and cross-functional teams to design experiments, interpret results, and advance program objectives.
• Support the development and implementation of robust, reproducible LNP production and characterization workflows.
• Maintain accurate and thorough documentation of experimental procedures, results, and conclusions in electronic laboratory notebooks.
• Analyze and communicate experimental results and present findings and recommendations to cross-functional teams.
• Contribute to a culture of scientific rigor, collaboration, continuous learning, and operational excellence.

Skills

Lipid nanoparticle formulation

LNP production

Process development

LNP characterization

Education

BS in chemical/biochemical engineering or related

MS in chemical/biochemical engineering or related

Tools

TFF equipment

Mixers & pumping systems

Job description

Mirai Bio, Inc. in Cambridge, MA is seeking a Senior Research Associate, LNP Production to design, produce, and optimize lipid nanoparticle formulations for preclinical lipid-based therapeutics.

The role requires hands-on experience with LNP formulation and production and collaboration across programs and partners. The successful candidate will contribute to the continuous improvement of Mirai Bio's delivery platform, working across scales and using pumps, mixers, and TFF to advance multiple