Senior LNP Production Scientist - Gene Delivery

Flagship Pioneering; Cambridge (MA); On-site; USD 81,000 - 107,000; Full time

Job summary

Mirai Bio in Cambridge, MA is seeking a Senior Research Associate, LNP Production to develop and advance lipid nanoparticle formulations for nucleic acid therapeutics. You will design, produce, characterize, and optimize LNPs to support preclinical research and the development of genetic medicines.

This hands-on role requires strong technical expertise in LNP formulation, robust experimental design, careful data documentation, and the ability to collaborate across programs to push delivery

Qualifications

• BS or MS in chemical engineering, biochemical engineering, pharmaceutical sciences, chemistry, biology, or a related scientific discipline
• BS + 5 years of relevant industry or research experience
• MS + 3 years of relevant industry or research experience

Responsibilities

• Design, formulate, produce, and characterize LNPs to support preclinical research for internal platform and external partnerships.
• Execute LNP production across a range of process scales, from small-scale formulation and process optimization through larger-scale production.
• Operate and develop processes using relevant LNP manufacturing and process-development equipment, including mixers, pumping systems, tangential flow filtration (TFF), and related technologies.
• Troubleshoot formulation and process challenges and contribute to the optimization and continuous improvement of LNP production processes.
• Collaborate closely with scientists and cross-functional teams to design experiments, interpret results, and advance program objectives.
• Support the development and implementation of robust, reproducible LNP production and characterization workflows.
• Maintain accurate and thorough documentation of experimental procedures, results, and conclusions in electronic laboratory notebooks.
• Analyze and communicate experimental results and present findings and recommendations to cross-functional teams.
• Contribute to a culture of scientific rigor, collaboration, continuous learning, and operational excellence.

Skills

LNP formulation

Data analysis

Collaboration

Experiment design

Communication

Education

BS or MS in chemical/biochemical engineering or related science

Tools

TFF systems

Pumps

Mixers

LNP processing equipment

Job description

Mirai Bio in Cambridge, MA is seeking a Senior Research Associate, LNP Production to develop and advance lipid nanoparticle formulations for nucleic acid therapeutics. You will design, produce, characterize, and optimize LNPs to support preclinical research and the development of genetic medicines.

This hands-on role requires strong technical expertise in LNP formulation, robust experimental design, careful data documentation, and the ability to collaborate across programs to push delivery