Protein Conjugation Scientist II

Alnylam Pharmaceuticals

United States

On-site

USD 68,000 - 101,000

Full time

4 days ago
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Job summary

Alnylam Pharmaceuticals in Cambridge, MA seeks an Associate Scientist-II to join the protein sciences team. The role focuses on protein production, purification, and conjugation with cross-functional collaboration across biology, chemistry, and pharmacology.

This lab-based, onsite position requires independence and motivation to drive multiple projects forward. The candidate should have experience in protein purification, bioconjugation, and analytical methods; familiarity with UV-Vis, HPLC, and

Qualifications

  • BS/MS in chemistry, biochemistry, or a related field with 0–1 years of lab experience.
  • Experience with modern bioconjugation chemistry and analytical techniques.
  • Experience with instrumentation such as Agilent and ÄKTA HPLC systems, TFF, and UV-Vis spectrometry.

Responsibilities

  • Deliver and validate proteins and protein conjugates at production scales.
  • Design, plan, and perform protein conjugation experiments for in vitro and in vivo evaluations.
  • Support purification, buffer exchange, and QC of protein conjugates using UV-Vis spectroscopy and HPLC.
  • Maintain laboratory infrastructure and collaborate with cross-functional teams.

Skills

Protein purification
Bioconjugation chemistry
Analytical techniques
HPLC
UV-Vis spectrometry
AKTA systems
Team collaboration
Independent work

Education

BS/MS in chemistry/biochemistry or related

Tools

Agilent HPLC
ÄKTA
TFF

Job description

Alnylam Pharmaceuticals in Cambridge, MA seeks an Associate Scientist-II to join the protein sciences team. The role focuses on protein production, purification, and conjugation with cross-functional collaboration across biology, chemistry, and pharmacology.

This lab-based, onsite position requires independence and motivation to drive multiple projects forward. The candidate should have experience in protein purification, bioconjugation, and analytical methods; familiarity with UV-Vis, HPLC, and

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