Pharma Manufacturing Operations Leader

Vertex Pharmaceuticals Inc (US); Tallahassee (FL); On-site; USD 139,000 - 209,000; Full time

Job summary

Vertex Pharmaceuticals Inc is seeking a Senior Manager, Manufacturing Operations to lead a supervisory team and ensure compliant, efficient cGMP manufacturing operations aligned with production schedules and site priorities.

The role requires building an audit-ready facility, driving continuous improvement, and delivering safe, high-quality drug products while coordinating with cross-functional teams across the site.

Qualifications

• Bachelor’s degree required in a scientific, technical, or engineering discipline.
• Typically requires 10+ years of experience or the equivalent combination of education and experience.
• Strong experience in direct people supervision in a cGMP manufacturing environment required.
• Significant leadership experience in pharmaceutical manufacturing operations within a cGMP-regulated environment required.

Responsibilities

• Manage and develop a supervisory team, ensuring strong execution, accountability, and team effectiveness.
• Oversee cGMP manufacturing activities, including equipment setup, assembly, operation, disassembly, cleaning, and associated support activities.
• Provide oversight for real-time on-the-floor batch record review and escalation of operational or compliance issues as needed.
• Participate in event investigations, CAPAs, and change controls in support of production and departmental objectives.
• Mentor, motivate, coach, and evaluate the performance of group members.

Skills

cGMP principles

cell therapy

QbD concepts

DoE

SPC

GMP systems

Education

Bachelor’s degree

Tools

QDoCCS

Job description

Vertex Pharmaceuticals Inc is seeking a Senior Manager, Manufacturing Operations to lead a supervisory team and ensure compliant, efficient cGMP manufacturing operations aligned with production schedules and site priorities.

The role requires building an audit-ready facility, driving continuous improvement, and delivering safe, high-quality drug products while coordinating with cross-functional teams across the site.