Senior Manufacturing Operations Leader

Vertex Pharmaceuticals Inc (US); United States; On-site; USD 139,000 - 209,000; Full time

Benefits offered by this job

Annual bonus

Equity awards

Comprehensive benefits

Paid time off

Job summary

Vertex Pharmaceuticals Inc. is seeking a Senior Manager, Manufacturing Operations to lead a supervisory team and oversee day-to-day cGMP manufacturing activities. You will drive safe, compliant production aligned with schedules and site goals, while maintaining audit-ready facilities and promoting continuous improvement.

Responsibilities include leading project efforts, managing batch documentation, and supporting validation and change control processes within a cross-functional environment.

Qualifications

• Bachelor's degree in scientific/engineering field.
• 10+ years of experience in cGMP manufacturing with supervisory responsibility.
• Strong leadership and ability to drive cross-functional teams.

Responsibilities

• Lead and develop a supervisory team for manufacturing operations.
• Ensure alignment with production schedules and site objectives.
• Oversee cGMP activities including equipment, documentation, and batch records.
• Participate in investigations, CAPAs, and change controls.
• Support validation activities, facility readiness, and compliance.
• Maintain audit-ready facility and drive continuous improvement.

Skills

Leadership

cGMP knowledge

Cell therapy

CAPA

SPC data

Cross-functional

Education

Bachelor's degree

Tools

QDoCCS

GMP systems

POMS MES

Job description

Vertex Pharmaceuticals Inc. is seeking a Senior Manager, Manufacturing Operations to lead a supervisory team and oversee day-to-day cGMP manufacturing activities. You will drive safe, compliant production aligned with schedules and site goals, while maintaining audit-ready facilities and promoting continuous improvement.

Responsibilities include leading project efforts, managing batch documentation, and supporting validation and change control processes within a cross-functional environment.