Immunology Discovery Scientist - Cell-Based Assays

BioSpace; Indianapolis (IN); On-site; USD 66,000 - 172,000; Full time

Job summary

Lilly's Immunology Discovery Research group in Indianapolis, IN is seeking a scientist to design and validate immunology cell-based assays that generate preclinical data for future therapeutics. You will work with human, monkey, and mouse lymphocytes, applying techniques like flow cytometry, ELISA, and qPCR in a collaborative, fast-paced environment.

The role requires a BS/MS in biology with 2–3 years of experience, strong immunology background, and experience with multi-color flow cytometry.

Qualifications

• B.S or M.S. in biology or related area with 2–3 years of work experience.
• Research experience in immunology and molecular biology; purification/handling primary human lymphocytes desirable.
• Basic understanding of high-parameter multi-color flow cytometry desirable.

Responsibilities

• Design, develop and validate immunology cell-based functional assays to deliver preclinical data.
• Isolate, purify and culture human, non-human primate and mouse lymphocytes for in vitro assays.
• Develop cellular activity assays using Western blot, qPCR, intracellular staining and phospho-flow cytometry.
• Investigate cytokine signaling and mechanism of action of biologics and small molecules.
• Perform siRNA knockdown and transfection in cell lines and primary cells; analyze and present data.

Skills

Immunology knowledge

Cell-based assays

Flow cytometry

Data analysis

Independent experiments

Education

B.S./M.S. in biology

Tools

Western blot

qPCR

ELISA

MSD multiplex

Confocal imaging

Job description

Lilly's Immunology Discovery Research group in Indianapolis, IN is seeking a scientist to design and validate immunology cell-based assays that generate preclinical data for future therapeutics. You will work with human, monkey, and mouse lymphocytes, applying techniques like flow cytometry, ELISA, and qPCR in a collaborative, fast-paced environment.

The role requires a BS/MS in biology with 2–3 years of experience, strong immunology background, and experience with multi-color flow cytometry.