Senior Research Officer (TBT Lab), IMCB

A*STAR RESEARCH ENTITIES; Singapore; On-site; SGD 20,000 - 60,000; Full time

Job summary

A leading research organization in Singapore is seeking a candidate to advance in vitro platforms for developmental neurotoxicity assessments. Responsibilities include establishing complex biological models and executing metabolomics analyses to support food safety. The role demands strong skills in cell culture and aims to generate regulatory-relevant data. This position is ideal for individuals interested in food safety and neurotoxicity evaluation.

Qualifications

• Experience in cell culture and cultivated cell production.
• Familiarity with developing biological models like organoids.
• Knowledge of metabolomics and high-throughput screening assays.

Responsibilities

• Contribute to development of advanced in vitro platforms for neurotoxicity assessment.
• Establish and optimise organoids and organ-on-chip systems.
• Design and execute analyses mapping adverse outcome pathways.

Job description

The role involves contributing to the development and implementation of advanced in vitro platforms for developmental neurotoxicity assessment relevant to food safety. The individual will be responsible for cultivated cell production, cell culture, and comprehensive cell characterisation to support toxicity and safety evaluation studies.

The role includes establishing and optimising complex biological models, such as organoids and organ-on-chip systems, to recapitulate key neurophysiological processes. In addition, the candidate will design and execute metabolomics analyses to map adverse outcome pathways, develop and apply high-throughput screening assays to detect both early and late indicators neurotoxicity. Ultimately, the goal is to generate robust, scalable, and regulatory-relevant data to support food safety risk assessment.