Scientist/Senior, Biotherapeutics Development (BTI)

Agency for Science, Technology and Research (A*STAR); Singapore; On-site; SGD 60,000 - 90,000; Full time

Job summary

A leading research agency in Singapore is seeking a motivated Scientist for their Biotherapeutics Development group. The role involves characterising monoclonal antibodies and contributing to the therapeutics development pipeline. Candidates should have a PhD in Biomedical Science or relevant disciplines and practical experience in various methodologies including in vivo studies and molecular biology techniques. Strong organisational skills and the ability to work collaboratively are essential. This position offers an opportunity to engage with industry partners and mentor interns.

Qualifications

• PhD degree in Biomedical Science, Cancer Science, Immunology, or relevant disciplines.
• Familiarity with requirements for selection of lead and hit candidates.
• Interest in translational and applied aspects of research.

Responsibilities

• Characterise and evaluate monoclonal antibodies for pre-clinical dossiers.
• Contribute to therapeutics development pipeline.
• Conduct in vivo studies like immunisations and tumour xenograft models.
• Work in project teams with collaborators.
• Mentor students and interns.
• Prepare presentation slides and reports.

Skills

Cell culture

Flow cytometry

Western blot

ELISA

Immunoprecipitation

Immunohistochemistry

Data analysis

In vivo studies

Education

PhD in Biomedical Science or relevant disciplines

Job description

Job Description

We are seeking a highly motivated Scientist to join our Biotherapeutics Development group. The successful candidate will contribute to research activities developing biotherapeutics with a goal towards clinical applications and commercialisation.

Key Responsibilities

• Characterise and evaluate monoclonal antibodies (mAbs), its antigen target and mechanism of action needed for a pre-clinical dossier
• Contribute to therapeutics development pipeline through hit and lead identification
• Conduct in vivo studies, such as immunisations and tumour xenograft models
• Work in project teams with internal and external collaborators
• Contribute to mentorship of students and interns
• Prepare presentation slides, reports, technology disclosures, grant proposals
• Maintain accurate and timely experimental records
• Support routine lab operations, including procurement, equipment maintenance, lab safety compliance, and general housekeeping

Job Requirements

• A PhD degree in Biomedical Science, Cancer Science, Immunology, or relevantdisciplines
• Familiar with the requirements needed for selection of potential lead and hit candidates
• A strong interest in the translational and applied aspects of research, including collaborations with industry partners.
• Practical experience in cellular and molecular biology (such as cell culture, flow cytometry, western blot, ELISA, immunoprecipitation, mammalian cell transfection, immunohistochemistry, bioassays, and data analysis) and in vivo studies
• Strong organisational and communication skills
• Able to work independently and collaboratively in a team