Research Assistant (Production Radiochemist)

NATIONAL UNIVERSITY OF SINGAPORE; Singapore; On-site; SGD 20,000 - 60,000; Full time

Job summary

A prominent research university in Singapore is seeking a knowledgeable Research Assistant (Production Radiochemist) to produce radiopharmaceuticals in a GMP-certified facility. This role involves performing radiolabelling procedures, preparing documentation, and ensuring compliance with safety regulations. Ideal candidates will have a BSc in a relevant field and technical expertise in laboratory techniques. The position offers a two-year contract with opportunities for professional growth. Reach out to Miss Emmalyn Chan Mei Mei for informal inquiries.

Qualifications

• Minimum of BSc degree in a relevant science discipline.
• Practical experiences in general laboratory techniques.
• Experiences in pharmaceutical production under GMP is an advantage.

Responsibilities

• Perform radiolabelling of peptides or small molecules.
• Prepare and review batch records and SOPs.
• Assist with maintenance of radiochemistry synthesis modules.

Skills

Analytical balance operations

Pipetting

pH measurement

Reagents preparation

Critical thinking

Problem-solving

High attention to detail

Education

BSc degree in Synthetic Organic/Inorganic/Medical Chemistry

Job description

Interested applicants are invited to apply directly at the NUS Career Portal

Your application will be processed only if you apply via NUS Career Portal

We regret that only shortlisted candidates will be notified.

Job Description

The National University of Singapore invites applications for Research Assistant (Production Radiochemist) in the Clinical Imaging Research Centre (CIRC), Yong Loo Lin School of Medicine. CIRC is a dedicated molecular imaging research centre. It is equipped with on-site capability for the preparation of PET radiopharmaceuticals in a state-of-the-art GMP-certified facility. CIRC is positioned to support both academic and commercially led clinical research programs, with dedicated clinical imaging facilities area advanced modalities of PET-CT and PET-MRI. For more details on what we do, do visit https://medicine.nus.edu.sg/circ/. Appointments will be made on a two-years contract basis with the possibility of extension.

Purpose of the post

The Production Radiochemist at Clinical Imaging Research Centre (CIRC) is responsible for the routine production of radiopharmaceuticals inside the Clean Room environment, in compliance with Good Manufacturing Practice (GMP). The Radiochemist will be assisting in the method development and validation of new radiopharmaceuticals, including the preparation of standard operating procedures (SOPs) and other quality documentation. With strong technical and analytical expertise, the Production Radiochemist helps maintain high operational uptime, ensures regulatory compliance, and upholds patient and product safety standards.

Main duties and responsibilities

The Production Radiochemist will be able to:

1. Perform radiolabelling of peptides, antibodies, or small molecules using radionuclides such as Lu-177, Ga-68, F-18, etc.
2. Prepare and review batch records, lab notebooks, SOPs and other documents.
3. Assist with emergency maintenance/calibration of radiochemistry synthesis and dispensing modules (e.g., Scintomics, iPhase, Trasis).
4. Support deviation investigations, CAPAs, and change control implementations as needed.
5. Perform ad-hoc clean room activities, including cleaning of rooms, stock inventory and environmental monitoring.
6. Safe handling of radioactive materials including hazardous waste disposal.
7. Working flexible hours, shifts, or weekends based on production schedules and isotope half-lives.
8. Performing any other duties as assigned by the Head of Department in accordance with GMP and safety regulations.

Physical Demands and Work Environment

Personnel should be:

• Willing to work with radioactive materials
• Able to read, listen and understand technical direction and procedures
• Able to lift heavy loads (up to 14kg with both hands)

Qualifications

The applicant should:

1. Have a minimum of BSc degree in Synthetic Organic/ Inorganic/ Medical Chemistry or a related science discipline;
2. Practical experiences in general laboratory techniques, such as analytical balance operations, pipetting, pH measurement and reagents preparation.
3. Experiences in pharmaceutical production under Good Manufacturing Practice (GMP) is an added advantage.
4. Experiences in radiolabelling and purification techniques with short-lived radioisotopes (F-18, C-11, Ga-68) or Lu-177 is highly desirable.
5. Proven ability to work independently with minimum supervision as well as a constructive team player.
6. Requires critical thinking and problem-solving skills
7. High attention to detail and commitment to data integrity.
8. Those with no experience but with relevant academic and skills will be considered for this position
9. Ability to perform first-line troubleshooting and minor repairs on automated modules (e.g., replacing tubing, valves, connectors, heaters).
10. Ability to read technical manuals, interpret wiring diagrams, and communicate effectively with engineers or vendors for equipment servicing.

Remuneration will be commensurate with the candidate’s qualifications and experience. Informal enquiries are welcome and should be made to Miss Emmalyn Chan Mei Mei at [e-mail].

Formal application: Please submit your application, indicating current/expected salary, supported by a detailed CV (including personal particulars, academic and employment history, complete list of publications/oral presentations and full contacts of three (3) referees to the NUS Career Portal.

We regret that only shortlisted candidates will be notified.