Senior Scientist - DMPK Bioanalysis

AstraZeneca; Cambridge; On-site; GBP 80,000 - 100,000; Full time

Job summary

A global pharmaceutical leader seeks a Senior Scientist in DMPK Bioanalysis to join their Oncology team in Cambridge. The role involves generating bioanalytical data, analyzing drug levels, and collaborating with cross-functional teams to advance innovative cancer therapies. Ideal candidates will have experience in bioanalysis and a collaborative mindset. Competitive salary and benefits offered.

Benefits

Flexible work environment

Career development opportunities

Inclusive workplace culture

Qualifications

• Proven experience in bioanalysis, DMPK, analytical chemistry, or pharmacology.
• Ability to communicate technical findings clearly.
• Strong attention to scientific integrity.

Responsibilities

• Lead studies generating high-quality bioanalytical data.
• Analyze drug levels in biological samples.
• Collaborate across teams to guide project decisions.

Skills

Experience in bioanalysis

Knowledge of LC-MS/MS

Attention to quality and detail

Collaborative mindset

Tools

LC-MS/MS

ICP-MS

Job description

Job Title

Senior Scientist – DMPK Bioanalysis (Oncology)
Location: The Discovery Centre, Cambridge, UK
Salary: Competitive + excellent benefits

About AstraZeneca

At AstraZeneca, we don’t just follow the science — we lead it. Every day, we push boundaries to deliver the next generation of cancer medicines faster and smarter.

We’re a global, science-driven company with a bold ambition: to transform cancer care and eliminate cancer as a cause of death. In Oncology, we take on some of the toughest challenges in medicine, using cutting-edge science, advanced technologies, and strategic partnerships to accelerate progress.

Here, you’ll be part of a team that’s fearless in pursuit of innovation — where your ideas matter, your work has real impact, and your curiosity is encouraged at every step.

About the role

We’re looking for a curious and collaborative Senior Scientist with a passion for DMPK bioanalysis to join our Oncology team in Cambridge.

In this role, you’ll help move new cancer therapies forward by providing essential insights into drug exposure and pharmacokinetics. Working closely with cross-functional partners, you’ll contribute directly to discoveries that improve patients’ lives. This is more than a job — it’s a chance to do work that matters, alongside people who care.

Accountabilities

• Lead and support studies that generate high-quality bioanalytical data.
• Use LC-MS/MS, ICP-MS, and other tools to analyze drug levels in biological samples.
• Prepare and optimize samples for analysis across a variety of biological matrices.
• Collaborate across Chemistry, Pharmacology, and PK Modelling teams.
• Share clear, actionable insights that guide project decisions.
• Drive innovation in bioanalytical methods and support best practices.
• Support and mentor colleagues, contributing to a learning culture.

Essential Skills

• Experience in bioanalysis, DMPK, analytical chemistry, or pharmacology.
• Practical knowledge of LC-MS/MS and in-vitro ADME techniques.
• Ability to communicate technical findings in a clear, solution-focused way.
• A collaborative mindset and a willingness to learn from others.
• Strong attention to quality, detail, and scientific integrity.
• Openness to exploring new approaches and challenging the status quo.

Desirable Skills

• Working on oncology pipelines or projects.
• Familiarity with novel modalities such as ADCs or targeted therapies.
• Experience with high-resolution mass spectrometry or radioisotopes.
• Publishing or presenting scientific work.

Why it’s great to work here

At AstraZeneca, we’re committed to helping you thrive — both professionally and personally. You’ll be supported to grow in your role, expand your skills, and shape a career that inspires you.

You’ll join a team that values openness, trust, and collaboration. We create space for every voice to be heard and every background to be respected — because we know diverse teams make better decisions and drive better science.

We also understand the importance of flexibility and work-life balance, offering an environment where you can do your best work in a way that works for you.

AstraZeneca is proud to be an equal opportunity employer. We’re building a team as diverse as the patients and communities we serve — and a workplace where everyone feels they belong.

Where can I find out more?

Our Social Media:

• Follow AstraZeneca on LinkedIn
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• Follow AstraZeneca on Instagram

Date Posted 04-Sep-2025

Closing Date 27-Sep-2025

Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.