Senior Scientist 2 (12-month fixed term contract)

BioLegend, Inc.; Cambridge; On-site; GBP 50,000 - 70,000; Full time

Job summary

A biomedical company in Cambridge seeks a Senior Scientist 2 to advance CHO-based expression technologies for biotherapeutics. This hands-on role involves leading research projects, mentoring junior scientists, and fostering collaboration across teams. Candidates should hold a Ph.D. in life sciences and have extensive experience in CHO cell line development and molecular biology. Join this innovative team to help shape biotherapeutic production technologies globally.

Qualifications

• Minimum 5 years of experience in a relevant scientific discipline.
• In-depth knowledge of CHO cell line development.
• Strong analytical skills and problem-solving abilities.

Responsibilities

• Lead research projects to develop new CHOSOURCE platform features.
• Mentor junior scientists.
• Maintain laboratory documentation and develop operating procedures.

Skills

Knowledge of CHO cell line development

Molecular biology expertise

Analytical mindset

Team collaboration

Education

Ph.D. in life science (molecular biology, biochemistry, cell biology or genetics)

Tools

PCR

ddPCR

Design of Experiment (DoE)

Job description

Senior Scientist 2- Bioproduction R&D- (12-month fixed-term contract)

Revvity's R&D Bioproduction department pioneers advanced expression platforms that power the manufacturing of next-generation biotherapeutics. Our portfolio includes specialized mammalian host cell lines, our innovative transposon-based expression system for rapid identification of high-expressing clones, and gene editing capabilities that enable custom cell line engineering. These technologies support both protein-based therapeutics and viral vector production, addressing the evolving needs of the biopharma industry.

Job summary

Join Revvity's Bioproduction R&D team as a Senior Scientist 2, where you'll drive innovation in our CHOSOURCE Expression platform. This is a hands-on, lab-based product development role focused on advancing CHO-based expression technologies for biotherapeutic production. You'll tackle real-world expression challenges, from optimizing productivity to enabling successful expression of diverse biologics and translate your findings into commercial products that empower biopharma customers worldwide.

Key responsibilities

• Lead independent research projects to develop and validate new CHOSOURCE platform features for both stable and transient expression applications, from experimental design through execution, analysis, and troubleshooting
• Mentor junior scientists through training, troubleshooting, and data review
• Foster collaborative relationships within the team and across Revvity departments
• Maintain comprehensive laboratory documentation and develop standard operating procedures
• Present clear, concise data at both internal and external meetings
• Support IP generation and regulatory documentation as needed for product commercialization

Essential Competencies & Requirements

• Ph.D. in life science (molecular biology, biochemistry, cell biology or genetics) plus minimum 5 years of demonstrated experience in a relevant scientific discipline
• In-depth knowledge of CHO cell line development, including stable pool generation, single cell cloning, and clone screening
• Previous experience in transient expression systems and optimization would be a plus
• Practical understanding of the challenges associated with expressing diverse biologics Advanced molecular biology skills, including expertise in diverse cloning methods (Gibson assembly, Golden Gate assembly), PCR, qPCR, and ddPCR
• Experience applying Design of Experiment (DoE) methodologies to experimental design
• Strong analytical mindset with ability to troubleshoot complex technical problems systematically
• Proven ability to work effectively in cross-functional, fast-paced environments
• Exceptional team collaboration skills with strong communication abilities and meticulous attention to detail
• Demonstrated scientific curiosity with a proactive approach to knowledge development

Join our team and help shape the future of biotherapeutic production technologies at Revvity.