Senior Principal Scientist Global Safety

Dechra Limited; Remote; GBP 70,000 - 90,000; Full time

Job summary

A global veterinary pharmaceuticals specialist based in the UK is seeking a Safety Technical Lead to effectively implement safety strategies for drug development. The ideal candidate will possess a PhD with substantial experience or a Master's degree with extensive industry knowledge. Responsibilities include managing safety assessments, liaising with regulatory agencies, and mentoring junior staff. This position emphasizes the need for strong analytical skills and experiences in non-clinical development within the veterinary sector.

Qualifications

• PhD in scientific field with significant industry experience or equivalent.
• Demonstrated success in non-clinical drug development.
• Strong analytical and influencing skills.

Responsibilities

• Serve as the Safety Technical Lead in Project Teams.
• Manage internal and external resources for safety strategies.
• Prepare and present data to regulatory agencies on drug safety.

Skills

Safety strategy implementation

Knowledge of regulatory requirements

Risk assessment skills

Mentoring abilities

Experience with Good Laboratory Practices (GLP)

Education

PhD in scientific field with 7 years experience or Master's with 15 years

Board certification in toxicology (DABT, ERT)

Job description

About the Position

So, what will you be doing? This role has a broad and varied remit and the successful candidate will have responsibility for duties including:

• Serves as the Safety Technical Lead in Project Teams to define and implement safety strategy
• Has knowledge of regulatory requirements for safety and toxicology testing for drug development, preferably in the veterinary space, and serves as a resource for this information, ensuring that appropriate elements of safety and toxicity are addressed in data collected to support regulatory submissions
• Directs and delivers the design, execution, interpretation, and reporting of safety studies
• Responsible for the preparation of animal and human health risk assessments using where appropriate established requirements and the generation of toxicological data required to establish MOE, ADI, POD, and MRL values
• Manages both internal and external resources for the execution of safety strategies
• Responsible for presentations or discussions with VMD, EMA, FDA and other relevant regulatory agencies on issues related to safety; prepares data reviews or position papers to resolve regulatory issues pertaining to drug safety
• Responsible for the preparation of drug submissions for Veterinary Medicinal Products / New Animal Drugs
• May serve as a Project Lead to progress projects through Research and Development
• May contribute to the safety evaluation of new pipeline opportunities through close collaboration with Business Development
• May perform safety risk assessments to determine the impact of quality deviations for marketed veterinary products
• May serve as a mentor to more junior personnel
• Publishes research in peer reviewed publications, and presents research at internal and external scientific venues, as appropriate

Diversity and Inclusion

Here at Dechra we pride ourselves on being an inclusive employer and we embrace candidates from all walks of life.

Qualifications

• PhD in scientific field with a minimum of 7 years relevant industry experience or a Master's degree with a minimum of 15 years relevant experience
• Demonstrated experience in non-clinical drug development
• Knowledge of Good Laboratory Practices (GLP)
• Ability to work independently with minimal oversight
• Ability to balance risk taking, opportunities and probability of success
• Ability to influence through persuasion

Desirable Qualifications

• Board certification in toxicology (DABT, ERT) preferred

Company Overview

We are a growing, global specialist within the world of veterinary pharmaceuticals. Our expertise is in the development, manufacture, marketing and sales of high quality products exclusively for veterinarians worldwide. Here at Dechra, our values are embedded within our culture and thrive within our family of almost 3000 colleagues globally. From manufacturing to marketing, (D)edication, (E)njoyment, (C)ourage, (H)onesty, (R)elationships and (A)mbition are at the heart of our everyday operations and the way we do business. This role can be performed remotely in any European Dechra entity.

Thanks for checking out our vacancy, we’re delighted you want to learn more about Dechra. The Opportunity Dechra is a UK-based, global business involved in the development and marketing of veterinary products primarily for dogs, cats, horses. Global Safety at Dechra provides safety expertise for early-stage drug development programs through to marketed products.