On-site Monitor * based in UK *

Syneos Health, Inc.; Greater London; On-site; GBP 35,000 - 50,000; Full time

Job summary

A leading biopharmaceutical solutions organization in London is seeking an experienced site management professional to ensure compliance with standard operating procedures and local regulations. The role requires excellent organizational and communication skills, along with the ability to work independently and within a team. Ideal candidates will have at least 1 year of relevant on-site monitoring experience and proficiency in English. As part of a diverse team, you will contribute to the success of clinical studies and the improvement of patients' lives globally.

Benefits

Career development opportunities

Supportive management

Diversity in workplace culture

Qualifications

• Minimum 1 year relevant on-site monitor experience.
• Very high level of English language required.
• Knowledge of local requirements for Real World Late Phase study designs.

Responsibilities

• Perform site management activities in compliance with SOPs.
• Assure compliance with local regulations depending on study.
• Conduct site management activities as per agreed Scope of Work.

Skills

English proficiency

Communication skills

Time management

Organizational skills

Customer service skills

Problem solving

Education

BA/BS in science/health care field or nursing degree

Tools

Microsoft Office Suite

Clinical Trial Management Systems

EDC systems

Job description

Updated: December 3, 2025
Location: London, LND, United Kingdom
Job ID: 25101909

Syneos Health® is a leading fully integrated biopharmaceutical solutions organization built to accelerate customer success. We translate unique clinical, medical affairs and commercial insights into outcomes to address modern market realities.

Our Clinical Development model brings the customer and the patient to the center of everything that we do. We are continuously looking for ways to simplify and streamline our work to not only make Syneos Health easier to work with, but to make us easier to work for.

Whether you join us in a Functional Service Provider partnership or a Full‑Service environment, you’ll collaborate with passionate problem solvers, innovating as a team to help our customers achieve their goals. We are agile and driven to accelerate the delivery of therapies, because we are passionate to change lives.

Discover what our 29,000 employees, across 110 countries already know:

WORK HERE MATTERS EVERYWHERE

Why Syneos Health

• We are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program.
• We are committed to our Total Self culture – where you can authentically be yourself. Our Total Self culture is what unites us globally, and we are dedicated to taking care of our people.
• We are continuously building the company we all want to work for and our customers want to work with. Why? Because when we bring together diversity of thoughts, backgrounds, cultures, and perspectives – we’re able to create a place where everyone feels like they belong.

Job Responsibilities

• Perform site management activities in compliance with the Company and Sponsor (if applicable) Standard Operating Procedures (SOPs) and Work Instructions (WIs).
• Assure compliance with local regulations and appropriate guidance depending on assigned study design / classification. May include Good Pharmacoepidemiology Practices (GPP) and/or International Conference on Harmonization Good Clinical Practice (ICH‑GCP).
• Conduct site management activities as per agreed Scope of Work (SoW), Site Management Plan (SMP) and relevant guidelines.
• Site identification – may contact sites to obtain interest in study participation, confirm contact details, retrieve documents for consideration, etc.
• Site Qualification – Ensures selection of appropriate sites for assigned studies.
• Site Start‑Up – With minimal supervision, ability to perform activities for assigned sites working with study start‑up and regulatory.
• Conduct of all remote and on‑site monitoring activities through all study stages.
• Routinely review the Investigator Site File (ISF) for accuracy, timeliness and completeness; reconcile contents of the ISF with the Trial Master File (TMF).
• Document activities via confirmation letters, follow‑up letters, trip reports, communication logs, and other required project documents as per SOPs and SMP, within required timelines. Supports subject/patient recruitment, retention and awareness strategies. Enter data into tracking systems as required to track all observations, ongoing status and assigned action items to resolution.
• Demonstrate diligence in protecting the confidentiality of each subject/patient.
• Assist with data query resolution and missing data follow‑up. Review data using data trend reports and knowledge of site practices. Ensure the resolution of data queries within agreed timelines. Utilize available hardware and software to support effective study data collection and review.
• Maintain effective, accurate and timely communication with site staff and project team, and ensure appropriate issue escalation and resolution as per SOPs with a focus on issue prevention.
• Maintain clinical tracking and management systems.
• Ensure all assigned sites are trained and compliant with requirements of the study protocol, informed consent process, data collection requirements/data collection tools and safety reporting.
• Provide guidance at the site and project level towards audit readiness standards and support preparation for audit and required follow‑up actions.
• Prepare for, attend and participate in Investigator Meetings and/or sponsor face‑to‑face meetings.
• Collaborate and build relationships with Sponsor affiliates, medical science liaisons, and local country sponsor staff, as required.
• Understand project scope, budgets, and timelines; manage site‑level activities/communication to ensure project objectives, deliverables and timelines are met. Adapt quickly, with oversight of the Clinical Operations Lead or designee, to changing priorities to achieve goals/targets.
• Identify and communicate out‑of‑scope activities to Clinical Operations Lead.
• Attend, contribute to and present at study and department meetings.

Qualifications

• BA/BS degree in science/health care field or nursing degree or equivalent combined education and experience.
• Proficiency in Microsoft Office Suite (Word, Excel, PowerPoint), email/voicemail, and Clinical Trial Management and EDC systems.
• Minimum 1 year relevant on‑site monitor experience.
• Very high level of English language required.
• Excellent communication, time management, organizational, documentation and customer service skills.
• Knowledge of local requirements for Real World Late Phase study designs as well as Real World Research and relevant regulations including GPP.
• Excellent customer focus (internal and external) and ability to interact professionally with a client organization and study site.
• Willingness to work within a team‑oriented environment; ability to work in a “virtual” team setting as well as work independently, seeking guidance as appropriate.
• Ability to handle multiple tasks (across multiple studies as necessary) and prioritize accordingly to achieve study timelines. Sound problem solving and analytical skills.
• Excellent command of written and spoken local language, if not English, as well as English required.
• Ability to develop good working relationships via oral communication and good phone etiquette.
• Ability to travel up to 60% on a regular basis depending on assignments and study phase.

Get to know Syneos Health

Over the past 5 years, we have worked with 94% of all Novel FDA Approved Drugs, 95% of EMA Authorized Products and over 200 Studies across 73,000 Sites and 675,000+ Trial patients.

No matter what your role is, you’ll take the initiative and challenge the status quo with us in a highly competitive and ever‑changing environment. Learn more about Syneos Health.

Tasks, duties, and responsibilities as listed in this job description are not exhaustive. The Company, at its sole discretion and with no prior notice, may assign other tasks, duties, and job responsibilities. Equivalent experience, skills, and/or education will also be considered so qualifications of incumbents may differ from those listed in the Job Description. The Company, at its sole discretion, will determine what constitutes as equivalent to the qualifications described above. Further, nothing contained herein should be construed to create an employment contract. Occasionally, required skills/experiences for jobs are expressed in brief terms. Any language contained herein is intended to fully comply with all obligations imposed by the legislation of each country in which it operates, including the implementation of the EU Equality Directive, in relation to the recruitment and employment of its employees. The Company is committed to compliance with the Americans with Disabilities Act, including the provision of reasonable accommodations, when appropriate, to assist employees or applicants to perform the essential functions of the job.

Discover what our more than 29,000 employees already know: work here matters everywhere. We work hard, and smart, all in the name of getting much‑needed therapies to those who need them most. A career with Syneos Health means your everyday work improves patients’ lives around the world. Selecting us as an employer secures a career in which you’re guaranteed to: