Director, Head of Bioinformatics for Immunology

PowerToFly; Cambridge; On-site; GBP 120,000 - 160,000; Full time

Job summary

A leading biopharmaceutical company in Cambridge is seeking a Director, Head of Bioinformatics for Immunology. This pivotal role drives innovative research and data-driven insights crucial for target identification and therapeutic development. The ideal candidate will possess a PhD in bioinformatics or a related field, paired with substantial experience in leading teams and applying AI/ML techniques. The position offers competitive compensation and opportunities for impactful work in drug discovery across various therapeutic areas.

Benefits

Comprehensive benefits package

Paid time off

401(k) options

Qualifications

• 8+ years of industry/academic experience in bioinformatics or related fields.
• Proven ability to lead interdisciplinary research teams.
• Extensive experience applying AI/ML in drug discovery.

Responsibilities

• Lead drug discovery through data-driven insights in immunology.
• Foster high performance and collaboration within the team.
• Drive integration of computational insights into therapeutic development.

Skills

Leadership

AI/ML techniques

Bioinformatics expertise

Collaboration skills

Genetic analysis

Education

PhD in bioinformatics or related field

Master's degree with extensive experience

Tools

Computational biology software

Job description

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok.

Job Description

The role of Director, Head of Bioinformatics for Immunology in Quantitative Medicine and Genomics (QM&G) is pivotal for driving data‑driven insight for target identification and validation, biomarker discovery, clinical development, forward and reverse translation, therapeutic innovation, and manufacturing within the QM&G functional area and across R&D. This role is responsible for leading a distributed team that leverages cutting‑edge bioinformatics to derive novel insights for end‑to‑end drug discovery and development; while the position is focused primarily in Immunology there are also opportunities for cross‑collaboration in multiple therapeutic areas, including, Aesthetics, Specialty Medicine, Biotherapeutics, Manufacturing Science and Technology.

Key Responsibilities

• Accelerate AbbVie’s drug discovery and development pipeline by establishing forward‑thinking informatics strategies and executing on results for multiple disease areas within Immunology
• Lead a dynamic team of bioinformaticians, and data scientists. Foster a culture of high performance and professional growth, ensuring the team operates at the cutting‑edge of scientific research and development.
• Spearhead innovative computational systems biology initiatives to revolutionize the discovery of therapeutic targets. Integrate insights from genetic, multi‑omics, and functional genomics data to drive innovation in therapy development.
• Oversee the application of AI/ML methods in both Discovery and clinical Development. Enable reverse translation leveraging cross‑sectional, multi‑modal clinical data analysis and method development.
• Optimize genetic medicine and biotherapeutics manufacturing capabilities through advanced computational insights and AI/ML applications, enhancing the efficacy and scalability of the next‑generation therapeutic approaches.
• Foster strong collaborations within the Bioinformatics community and across R&D, clinical teams, and other departments to ensure bioinformatic and genetic insights are effectively integrated into AbbVie's pipeline programs.
• Cultivate and lead partnerships with academic institutions, biotechnology companies, and technology providers. Drive the evaluation and integration of emerging technologies and methodologies, enhancing team capabilities and keeping AbbVie at the helm of scientific progress.

Qualifications

• PhD in bioinformatics, statistics, mathematics, computer science, computational biology, genomics, or a related field with 8+ years industry/academic experience.
• Or master’s degree with 15+ years of relevant experience.
• Proven success of managing, leading, and mentoring interdisciplinary teams in large‑scale research environments, demonstrating exceptional management and leadership capabilities.
• Extensive experience applying AI/ML techniques in drug discovery and development to drive innovation and therapeutic outcomes, with proven results and impact.
• Deep expertise in transcriptomics and proteomics, encompassing bulk, single‑cell, and spatial approaches, and multi‑omic integration methodologies.
• Proficient in genetic analysis techniques, including GWAS, QTL, genetic risk modeling, and multi‑omics integration, with a focus on actionable insights.
• Strong background in target identification, biomarker discovery, and clinical translation, aimed at enhancing therapeutic development processes.
• Demonstrated ability to collaborate cross‑functionally, with experience in working with clinical teams and translating complex computational findings into clinical insights for diverse teams.
• Adept at articulating complex scientific concepts to non‑scientific stakeholders and executive leadership, ensuring clarity and strategic alignment.

Additional Information

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.

• This job is eligible to participate in our short‑term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company’s sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: https://www.abbvie.com/join-us/reasonable-accommodations.html

What AbbVie Has to Offer

Our work can—and does—have a tangible, lasting impact on millions of people. But it’s not just the results that matter. How we achieve them matters, too. Leading with purpose, we work to build a more sustainable future for generations to come. We do that by putting our expertise, resources and talent to work to make a real difference for patients, communities and our world.