Clinical Operations Manager

University College London Hospitals NHS Foundation Trust; City of Westminster; On-site; GBP 60,000 - 80,000; Full time

Job summary

A leading healthcare organization in the UK seeks a Clinical Operations Manager to oversee the epilepsy clinical trials portfolio. The role involves managing trial setup and delivery, collaboration with researchers, and ensuring compliance with regulatory standards. The ideal candidate will demonstrate leadership and problem-solving abilities, contributing to innovation in clinical research. This position is based at two prominent hospitals in London and Buckinghamshire.

Qualifications

• Experience in managing clinical trials in a research environment.
• Strong knowledge of Good Clinical Practice (GCP) and regulatory requirements.
• Ability to manage and develop staff effectively.

Responsibilities

• Lead the delivery of epilepsy clinical trials across two major sites.
• Oversee trial set-up, monitoring, and ensure regulatory compliance.
• Manage recruitment, training, and development of research delivery teams.

Skills

Leadership

Problem-solving

Collaboration

Operational management

Financial expertise

Job description

Overview

We are seeking an experienced and solutions-focused Clinical Operations Manager to lead the epilepsy clinical trials portfolio at the National Hospital for Neurology and Neurosurgery (NHNN). This is an excellent opportunity for a motivated leader with strong operational, financial, and governance expertise to shape the future of epilepsy research across two internationally recognised sites. Based across NHNN Queen Square (London) and the Chalfont Centre for Epilepsy (Buckinghamshire), you will oversee study setup, trial delivery, and financial sustainability of both commercial and non-commercial trials, working closely with Principal Investigators, Senior Research Nurses, and the UCL/UCLH Joint Research Office. This is a strategic yet hands-on role where you will strengthen trial capacity, accelerate setup timelines, and ensure high-quality, compliant delivery. You will also line manage members of the research delivery team, supporting staff recruitment, development, and workload allocation. Acting as a key contact for investigators, sponsors, CROs, and regulators, you will represent UCLH as a leading site for epilepsy research.

Responsibilities

• As Clinical Operations Manager, you will lead the delivery of a diverse portfolio of epilepsy clinical trials across NHNN Queen Square (London) and the Chalfont Centre for Epilepsy (Buckinghamshire).
• You will take responsibility for driving trial set-up, monitoring progress, and ensuring studies are delivered safely, on time, and to the highest regulatory standards.
• You will line manage research nurses and guide the wider research delivery team, supporting recruitment, training, and development to build a motivated and skilled workforce.
• A key part of your role will be strengthening collaboration with investigators, industry partners, and regulators, while ensuring the financial sustainability of the portfolio through accurate and timely income recovery.
• This is a role for someone who thrives on leadership and problem-solving. Whether streamlining trial processes, guiding staff, or representing UCLH at national and industry forums, you will be central to advancing research that improves the lives of people with epilepsy.

Ideal candidate

• The ideal candidate will combine leadership with problem-solving skills, thrive in collaboration, and be motivated to drive innovation in clinical research.
• You will ensure studies are delivered safely, efficiently, and in line with GCP and regulatory requirements across both locations.

About UCLH

University College London Hospitals NHS Foundation Trust (UCLH) is one of the most complex NHS trusts in the UK, serving a large and diverse population. We provide academically led acute and specialist services, to people from the local area, from throughout the United Kingdom and overseas. Our vision is to deliver top-quality patient care, excellent education, and world-class research. We provide first-class acute and specialist services across eight sites:

• University College Hospital (incorporating the Elizabeth Garrett Anderson Wing), We are dedicated to the diagnosis and treatment of many complex illnesses. UCLH specialises in women\'s health and the treatment of cancer, infection, neurological, gastrointestinal and oral disease. It has world class support services including critical care, imaging, nuclear medicine and pathology.
• We are committed to sustainability and have pledged to become a carbon net zero health service, embedding sustainable practice throughout UCLH. We have set an ambitious target of net zero for our direct emissions by 2031 and indirect emissions by 2040.