Clinical Operations Manager

Mantell Associates; Remote; GBP 60,000 - 80,000; Full time

Job summary

A leading Biotech firm in the UK is looking for a motivated Clinical Operations Manager to oversee clinical trials. This fully remote role involves leading trial management, ensuring compliance with regulations, and coordinating teams to meet project milestones. Candidates should have 4-7 years of experience in clinical operations or related fields, manage multiple trials, and demonstrate excellent communication skills. The position offers flexibility and the chance to work on groundbreaking therapies.

Qualifications

• Minimum of 4-7 years’ experience in clinical operations.
• Strong knowledge of ICH-GCP and clinical trial regulations.
• Excellent communication and stakeholder management skills.

Responsibilities

• Lead operational aspects of clinical trials from start-up to close-out.
• Coordinate site selection, feasibility assessments, and vendor management.
• Oversee patient recruitment strategies and monitor trial progress.

Skills

Clinical trial management

Project management

Communication skills

Stakeholder management

Problem-solving

Job description

Mantell Associates is partnered with a forward-looking Biotech company, who is seeking a motivated and experienced Clinical Operations Manager to join their clinical development team on a contract basis. This fully remote UK-based role offers flexibility while playing a critical part in the execution and management of clinical trials that support breakthrough therapies.

Clinical Operations Manager - Responsibilities

• Lead and manage operational aspects of clinical trials from study start-up through close-out, ensuring timely delivery of milestones and adherence to regulatory and quality standards
• Coordinate site selection, feasibility assessments, site initiation, vendor management, and contracts, ensuring alignment with study protocols and timelines
• Oversee patient recruitment strategies, enrollment tracking, retention and retention-related logistics to meet study enrolment targets
• Monitor trial progress, manage timelines, budgets, and resources; work closely with Clinical Operations, Data Management, Safety / Pharmacovigilance, and Regulatory teams to ensure smooth execution
• Ensure compliance with ICH-GCP, national and international regulations, and company SOPs; maintain high standards of data integrity and patient safety
• Provide regular status reports, risk assessments, and contingency plans to senior leadership and stakeholders; proactively identify and manage operational risks
• Support vendor and CRO oversight, including performance monitoring, quality assurance, and deliverable tracking
• Facilitate cross-functional communication among clinical, regulatory, safety, and project teams to ensure coordinated execution and alignment of trial objectives
• Implement continuous process improvements - optimising workflows, documentation, and trial management procedures to boost efficiency and quality.

Clinical Operations Manager - Requirements

• Minimum of 4-7 years’ experience in clinical operations or related roles within biotech, pharma, or CRO settings, with direct involvement in clinical trial management
• Strong knowledge of ICH-GCP, clinical trial regulations (UK / EU), and regulatory requirements; experience working with multinational and remote trial teams is a plus
• Demonstrated ability to manage multiple trials or projects in parallel, with solid skills in planning, coordination, and problem-solving under tight timelines
• Excellent communication and stakeholder-management skills; comfortable interacting across cross-functional teams and external partners
• Proven record in site management, vendor or CRO oversight, and patient recruitment / retention strategies
• Ability to work independently and remotely, with self-motivation, discipline, and ability to drive projects to completion
• Based in the UK, with eligibility to work full time and ability to commit to contract duration

Mantell Associates is a specialist Pharmaceutical and Life Science headhunting firm. For more information on this opportunity, contact us at [phone].