Senior Computational Scientist

BioTalent Ltd; Paris; Sur place; EUR 80 000 - 100 000; Plein temps

Résumé du poste

A leading biotech firm in Paris is looking for a Senior Scientist to join their Protein & Vector Engineering team. This role focuses on advancing computational drug design through innovative approaches in structural bioinformatics, computational chemistry, and AI-driven methodologies. The successful candidate will lead computational strategies and collaborate with multidisciplinary teams. A PhD in a relevant discipline and over 5 years of experience in computational drug design are required. The position offers an exciting, collaborative environment geared toward cutting-edge research.

Qualifications

• 5+ years’ experience in computational drug design or molecular modelling.
• Strong expertise in structural bioinformatics and computational chemistry.
• Mentoring junior scientists is essential.

Responsabilités

• Lead computational strategies for drug design and molecular modelling.
• Design and execute advanced workflows in AI/ML-driven CDD.
• Collaborate with internal teams and external partners.

Connaissances

Structural bioinformatics

Computational chemistry

AI/ML expertise

Programming in Python

Molecular modelling

Formation

PhD in a relevant computational or life sciences discipline

Outils

Schrödinger

MOE

Rosetta

PyMOL

AlphaFold

Description du poste

We are seeking a Senior Scientist to join our Protein & Vector Engineering team, contributing to cutting‑edge research in structural bioinformatics, computational chemistry, and AI‑driven drug design.

This role plays a key part in advancing computational drug design (CDD) across biologics, chemistry, and genomics programmes. You will work closely with senior scientists and cross‑functional teams to develop and apply innovative computational approaches for 3D structure prediction, molecular modelling, and protein/antibody design.

What this role offers

• Senior‑level ownership of computational strategy and execution
• Exposure to AI‑ and computation‑driven drug discovery programmes
• A collaborative, multidisciplinary environment across protein engineering, genomics, and data science
• Opportunity to contribute to publications, patents, and platform development

Key responsibilities

• Lead computational strategies for drug design, molecular modelling, and structural bioinformatics
• Design and execute advanced workflows (MD, QM, protein & antibody design, AI/ML‑driven CDD)
• Mentor junior scientists and support technical development
• Build and maintain robust, reproducible in‑house computational pipelines
• Collaborate with internal teams and external partners

What you’ll bring

• PhD in a relevant computational or life sciences discipline
• 5+ years’ experience in computational drug design or molecular modelling
• Strong expertise in structural bioinformatics, computational chemistry, and AI/ML
• Programming skills in Python, R, or Bash
• Experience with tools such as Schrödinger, MOE, Rosetta, PyMOL, AlphaFold

Nice to have

• HPC or cloud computing experience
• Peptide modelling
• End‑to‑end drug discovery exposure